Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | PTGES | O14684 | 1/20 | 0.53 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.51 |
| ▸ | DUSP10 | Q9Y6W6 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.44 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14519736 | 0.81 | ALDH1A1 (0.55) | RAB9ASMN1; SMN2KMT2APTGESHSD11B1 | |
| SCHEMBL10633574 | 0.81 | HPGD (0.51) | RAB9ASMN1; SMN2KMT2ANPC1MEN1 | |
| SCHEMBL12868378 | 0.80 | ALDH1A1 (0.56) | FFAR1RAB9ASMN1; SMN2KMT2APTGES | |
| SCHEMBL10814768 | 0.80 | FFAR1 (0.61) | FFAR1SMN1; SMN2KMT2ANPC1MEN1 | |
| SCHEMBL677696 | 0.79 | MAOA (0.47) | RAB9ASMN1; SMN2KMT2APTGESHSD11B1 | |
| SCHEMBL6085096 | 0.78 | NPC1 (0.52) | RAB9AKMT2ANPC1HTTMAPT | |
| SCHEMBL7407 | 0.77 | FFAR1 (0.68) | FFAR1KMT2AHSD11B1NPC1MEN1 | |
| SCHEMBL13799728 | 0.77 | FFAR1 (0.52) | FFAR1RAB9ASMN1; SMN2KMT2ANPC1 | |
| SCHEMBL9179407 | 0.76 | FFAR1 (0.74) | FFAR1RAB9ASMN1; SMN2KMT2ANPC1 | |
| SCHEMBL74365 | 0.76 | FFAR1 (1.00) | FFAR1KMT2ANPC1MEN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210032229-A1 | PYRIDINE RING-SUBSTITUTED PYRIDAZINOL COMPOUNDS AND DERIVATIVES, PREPARATION METHODS, HERBICIDAL COMPOSITIONS AND APPLICATIONS THEREOF | QINGDAO KINGAGROOT CHEMICAL COMPOUND CO., LTD. (CN) | 2021-02-04 | — | — | US | disclosed |
| US-20210032222-A1 | FIVE-MEMBERED RING-SUBSTITUTED PYRIDAZINOL COMPOUNDS AND DERIVATIVES, PREPARATION METHODS, HERBICIDAL COMPOSITIONS AND APPLICATIONS THEREOF | QINGDAO KINGAGROOT CHEMICAL COMPOUND CO., LTD. (CN) | 2021-02-04 | — | — | US | disclosed |
| US-8895744-B2 | Alfa-carboline inhibitors of NPM-ALK, RET, and Bcr-Abl | UNIVERSITA' DEGLI STUDI DI MILANO-BICOCCA (IT) | 2014-11-25 | — | — | US | disclosed |
| US-8895744-B2 | Alfa-carboline inhibitors of NPM-ALK, RET, and Bcr-Abl | UNIVERSITA' DEGLI STUDI DI MILANO-BICOCCA (IT) | 2014-11-25 | — | — | US | disclosed |
| US-20110281862-A1 | ALFA-CARBOLINE INHIBITORS OF NPM-ALK, RET, AND BCR-ABL | UNIVERSITA' DEGLI STUDI DI MILANO - BICOCCA (IT) | 2011-11-17 | — | — | US | disclosed |
| US-20110152480-A1 | Catalysts for Polymerizing Olefins and Method Thereof | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2011-06-23 | — | — | US | disclosed |
| US-20110152480-A1 | Catalysts for Polymerizing Olefins and Method Thereof | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2011-06-23 | — | — | US | disclosed |
| US-20110152480-A1 | Catalysts for Polymerizing Olefins and Method Thereof | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2011-06-23 | — | — | US | disclosed |
| EP-2331589-A1 | CATALYSTS FOR POLYMERIZING OLEFINS AND METHOD THEREOF | Basell Poliolefine Italia S.R.L. (IT) | 2011-06-15 | — | — | EP | disclosed |
| WO-2010026184-A1 | CATALYSTS FOR POLYMERIZING OLEFINS AND METHOD THEREOF | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2010-03-11 | — | — | WO | disclosed |
| WO-2010026184-A1 | CATALYSTS FOR POLYMERIZING OLEFINS AND METHOD THEREOF | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2010-03-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210032229-A1 | PYRIDINE RING-SUBSTITUTED PYRIDAZINOL COMPOUNDS AND DERIVATIVES, PREPARATION METHODS, HERBICIDAL COMPOSITIONS AND APPLICATIONS THEREOF | CBR3, CBR1, H1-0 | FFAR1 1555/4885RAB9A 3172/4885SMN1; SMN2 3827/4885 |
| US-20110281862-A1 | ALFA-CARBOLINE INHIBITORS OF NPM-ALK, RET, AND BCR-ABL | ALK, BCR, NPM1 | FFAR1 1201/4885RAB9A 2539/4885SMN1; SMN2 3499/4885 |
| US-20210032222-A1 | FIVE-MEMBERED RING-SUBSTITUTED PYRIDAZINOL COMPOUNDS AND DERIVATIVES, PREPARATION METHODS, HERBICIDAL COMPOSITIONS AND APPLICATIONS THEREOF | CBR3, CBR1, CYP8B1 | FFAR1 982/4885RAB9A 1211/4885SMN1; SMN2 3292/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.