Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | COMT | P21964 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 4/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | AR | P10275 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
| ▸ | BCR | P11274 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALKBH3 | Q96Q83 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9775712 | 0.88 | AR (0.44) | COMTSMN1; SMN2LTA4HHTTL3MBTL1 | |
| SCHEMBL3411791 | 0.80 | CYP1A1 (0.45) | ACHETDP1KDM4EGAAMAPT | |
| SCHEMBL7017882 | 0.78 | CYP1A2 (0.41) | SMN1; SMN2HTTL3MBTL1TDP1ALDH1A1 | |
| SCHEMBL6777000 | 0.77 | CYP1A1 (0.41) | COMTSMN1; SMN2LTA4HACHEFFAR4 | |
| SCHEMBL9374193 | 0.76 | CYP11B2 (0.46) | SMN1; SMN2LTA4HHTTL3MBTL1ALDH1A1 | |
| SCHEMBL12770833 | 0.75 | ALKBH3 (0.57) | SMN1; SMN2LTA4HACHEFFAR4HTT | |
| SCHEMBL16059029 | 0.75 | MAOB (0.40) | LTA4HFFAR4L3MBTL1ALDH1A1GAA | |
| SCHEMBL13026669 | 0.74 | FFAR4 (0.57) | SMN1; SMN2FFAR4HTTL3MBTL1AR | |
| SCHEMBL10390673 | 0.74 | LTA4H (0.41) | LTA4HL3MBTL1ARMAPTNPSR1 | |
| SCHEMBL8093284 | 0.74 | HPGD (0.43) | SMN1; SMN2ACHEALDH1A1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6831081-B2 | Herpes virus including simplex types 1 and 2, varicella zoster, human cytomegalovirus, Epstein-Barr and human 6, 7 and 8 | PHARMACIA & UPJOHN | 2004-12-14 | — | — | US | disclosed |