Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6772980 | 0.91 | EDNRB (0.41) | EDNRAEDNRB | |
| SCHEMBL8056643 | 0.84 | EDNRA (0.43) | EDNRAEDNRB | |
| SCHEMBL6777479 | 0.81 | EDNRB (0.44) | EDNRAEDNRB | |
| SCHEMBL6772649 | 0.80 | TDP1 (0.34) | — | |
| SCHEMBL6776263 | 0.79 | EDNRA (0.46) | EDNRA | |
| SCHEMBL6777054 | 0.79 | EDNRA (0.46) | EDNRA | |
| SCHEMBL6771344 | 0.78 | EDNRB (0.43) | EDNRAEDNRB | |
| SCHEMBL4632109 | 0.77 | EDNRB (0.43) | EDNRAEDNRB | |
| SCHEMBL4770889 | 0.76 | EDNRB (0.40) | EDNRAEDNRB | |
| SCHEMBL4632432 | 0.76 | MAPT (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6673824-B1 | HYPOTENSIVE AGENTS | BRISTOL-MYERS SQUIBB CO. | 2004-01-06 | — | — | US | disclosed |
| US-6107320-A | Phenyl sulfonamide endothelin antagonists | BRISTOL-MYERS SQUIBB CO. (US) | 2000-08-22 | — | — | US | disclosed |