Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.46 |
| ▸ | TLR7 | Q9NYK1 | 10/20 | 0.42 |
| ▸ | TLR8 | Q9NR97 | 7/20 | 0.40 |
| ▸ | BMP1 | P13497 | 2/20 | 0.38 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | LTC4S | Q16873 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6776799 | 0.86 | TLR7 (0.39) | TLR7TLR8NUDT1 | |
| SCHEMBL6779814 | 0.82 | FAAH (0.47) | TLR7TLR8NUDT1 | |
| SCHEMBL6777954 | 0.81 | TLR7 (0.41) | TLR7TLR8NUDT1 | |
| SCHEMBL6775141 | 0.80 | TLR7 (0.51) | TLR7TLR8NUDT1 | |
| SCHEMBL6779049 | 0.80 | DRD2 (0.45) | TLR7TLR8OPRM1 | |
| SCHEMBL6778051 | 0.79 | TLR7 (0.46) | TLR7TLR8NUDT1 | |
| SCHEMBL6782828 | 0.79 | TLR7 (0.41) | TLR7TLR8NUDT1 | |
| SCHEMBL6777013 | 0.79 | TLR7 (0.44) | TLR7TLR8NUDT1 | |
| SCHEMBL6773648 | 0.79 | TLR7 (0.48) | TLR7TLR8NUDT1 | |
| SCHEMBL6782550 | 0.78 | TLR7 (0.40) | TLR7TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6720334-B2 | IMMUNE RESPONSE MODIFIERS; CYTOKINE BIOSYNTHESIS; VIRAL AND NEOPLASTIC DISEASES; 1-(4-(4-AMINO-6,7-DIMETHYL-1H-IMIDAZO (4,5-C)PYRIDIN-1-YL)BUTYL)-3-PHENYLUREA. | 3M INNOVATIVE PROPERTIES COMPANY | 2004-04-13 | — | — | US | claimed |