Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 12/20 | 0.46 |
| ▸ | TAS1R1 | Q7RTX1 | 12/20 | 0.46 |
| ▸ | BCL2L1 | Q07817 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6777938 | 1.00 | TAS1R3 (0.46) | TAS1R3TAS1R1BCL2L1 | |
| SCHEMBL6777746 | 0.90 | TAS1R3 (0.50) | TAS1R3TAS1R1BCL2L1 | |
| SCHEMBL6777750 | 0.90 | TAS1R3 (0.50) | TAS1R3TAS1R1BCL2L1 | |
| SCHEMBL6776372 | 0.87 | ADRB2 (0.41) | BCL2L1 | |
| SCHEMBL6776375 | 0.87 | ADRB2 (0.41) | BCL2L1 | |
| SCHEMBL6778269 | 0.86 | TAS1R3 (0.42) | TAS1R3TAS1R1 | |
| SCHEMBL6778272 | 0.86 | TAS1R3 (0.42) | TAS1R3TAS1R1 | |
| SCHEMBL6886588 | 0.85 | ALDH1A1 (0.50) | TAS1R3TAS1R1 | |
| SCHEMBL6886592 | 0.85 | ALDH1A1 (0.50) | TAS1R3TAS1R1 | |
| SCHEMBL6775099 | 0.85 | TAS1R3 (0.48) | TAS1R3TAS1R1BCL2L1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6693123-B2 | (4-(3-PYRIDYLAMINOMETHYLENE)-2-PHENYLBENZOYL)-N -METHYLMETHIONINE, METHYL ESTER FOR EXAMPLE; RESTENOSIS, HYPERPLASIA | UNIVERSITY OF PITTSBURGH | 2004-02-17 | — | — | US | disclosed |
| US-20020193596-A1 | Inhibitors of protein isoprenyl transferases | UNIVERSITY OF PITTSBURGH (US) | 2002-12-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020193596-A1 | Inhibitors of protein isoprenyl transferases | LANCL1, FNTB, DHCR7 | TAS1R3 4547/4885TAS1R1 4482/4885BCL2L1 3199/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.