SCHEMBL6777957

SCHEMBL6777957

O=C1CCCC(Sc2ccccc2Cl)C1C(=O)c1ccc2c(c1Cl)CCS2(=O)=O

nearest known ligand 0.36

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.32
HPGD P15428 1/20 0.32
HTT P42858 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6774106 0.91 DDB1 (0.35)
SCHEMBL6773992 0.90
SCHEMBL6772622 0.88 MCL1 (0.31)
SCHEMBL6769052 0.88 ITGB2 (0.31)
SCHEMBL6772834 0.87 CRBN (0.39) POLBHPGD
SCHEMBL6768450 0.83 GABRA1 (0.34)
SCHEMBL6771406 0.83 MCL1 (0.30)
SCHEMBL6773241 0.83
SCHEMBL6773873 0.82 CTSK (0.37)
SCHEMBL6772364 0.82 DDB1 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6756343-B1 CONTROLLING RICE PADDY FIELD WEEDS AT LOW DOSAGE DOSE; PLANT SAFENING IDEMITSU KOSAN CO., LTD. (JP) 2004-06-29 US disclosed
US-20040002425-A1 Triketone derivatives and herbicides IDEMITSU KOSAN CO., LTD. (JP) 2004-01-01 US disclosed
EP-1120413-A1 TRIKETONE DERIVATIVE AND HERBICIDE IDEMITSU KOSAN COMPANY LIMITED (JP) 2001-08-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040002425-A1 Triketone derivatives and herbicides SYMPK, STK36, STK32A POLB 1780/4885HPGD 2858/4885HTT 1264/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.