SCHEMBL6342144

SCHEMBL6342144

CCC(C)(C)c1cccc(-c2ccc(-c3ccccc3)cc2)c1C(C)(C)CC

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARG P37231 1/20 0.35
PPARA Q07869 1/20 0.35
PDCD1 Q15116 1/20 0.35
CD274 Q9NZQ7 1/20 0.35
SMN1; SMN2 Q16637 3/20 0.35
NPC1 O15118 1/20 0.35
LMNA P02545 1/20 0.35
MAPK1 P28482 1/20 0.35
CASP3 P42574 1/20 0.35
RAB9A P51151 1/20 0.35
ATM Q13315 1/20 0.35
SENP8 Q96LD8 1/20 0.35
SENP7 Q9BQF6 1/20 0.35
SENP6 Q9GZR1 1/20 0.35
TAAR1 Q96RJ0 2/20 0.33
DRD2 P14416 1/20 0.33
HTR7 P34969 1/20 0.33
L3MBTL1 Q9Y468 2/20 0.33
PTGS2 P35354 1/20 0.33
MAPT P10636 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12537526 0.84 PDCD1 (0.33) PPARGPPARAPDCD1CD274SMN1; SMN2
SCHEMBL127574 0.82 MAPK1 (0.41) PPARGPPARAPDCD1CD274SMN1; SMN2
SCHEMBL677798 0.80 MAPK1 (0.40) PPARGPPARAPDCD1CD274SMN1; SMN2
SCHEMBL6342145 0.80 MAPK1 (0.42) PDCD1CD274SMN1; SMN2NPC1LMNA
SCHEMBL10438750 0.79 PDCD1 (0.37) PPARGPPARAPDCD1CD274SMN1; SMN2
SCHEMBL9695975 0.79 PDCD1 (0.37) PPARGPPARAPDCD1CD274SMN1; SMN2
SCHEMBL26632610 0.78 HNF4A (0.43) PPARGPPARAPDCD1CD274SMN1; SMN2
SCHEMBL31510648 0.78 HNF4A (0.43) PPARGPPARAPDCD1CD274SMN1; SMN2
SCHEMBL780023 0.78 CA2 (0.37) SMN1; SMN2NPC1LMNAMAPK1CASP3
SCHEMBL6342141 0.77 SMN1; SMN2 (0.41) SMN1; SMN2NPC1LMNAMAPK1CASP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10662373-B2 Scintillating material composition to provide high light output NANOPTICS, INCORPORATED (US) 2020-05-26 US claimed
US-20170313935-A1 SCINTILLATING MATERIAL COMPOSITION TO PROVIDE HIGH LIGHT OUTPUT NANOPTICS, INCORPORATED 2017-11-02 US claimed
US-9657220-B2 Scintillating material composition to provide high light output NANOPTICS, INCORPORATED (US) 2017-05-23 US claimed
US-20150123036-A1 SCINTILLATING MATERIAL COMPOSITION TO PROVIDE HIGH LIGHT OUTPUT NANOPTICS, INCORPORATED 2015-05-07 US claimed
US-10662373-B2 Scintillating material composition to provide high light output NANOPTICS, INCORPORATED (US) 2020-05-26 US disclosed
US-20190072678-A1 MATERIALS, METHOD, AND APPARATUS FOR DETECTING NEUTRONS AND IONIZING RADIATION NANOPTICS, INCORPORATED 2019-03-07 US disclosed
EP-2689270-B1 MATERIALS, METHOD, AND APPARATUS FOR DETECTING NEUTRONS AND IONIZING RADIATION NANOPTICS INCORPORATED (US) 2018-12-05 EP disclosed
US-9897706-B2 Materials, method, and apparatus for detecting neutrons and ionizing radiation NANOPTICS, INCORPORATED (US) 2018-02-20 US disclosed
US-20170313935-A1 SCINTILLATING MATERIAL COMPOSITION TO PROVIDE HIGH LIGHT OUTPUT NANOPTICS, INCORPORATED 2017-11-02 US disclosed
US-9657220-B2 Scintillating material composition to provide high light output NANOPTICS, INCORPORATED (US) 2017-05-23 US disclosed
US-20150241573-A1 MATERIALS, METHOD, AND APPARATUS FOR DETECTING NEUTRONS AND IONIZING RADIATION NANOPTICS, INCORPORATED 2015-08-27 US disclosed
US-20150123036-A1 SCINTILLATING MATERIAL COMPOSITION TO PROVIDE HIGH LIGHT OUTPUT NANOPTICS, INCORPORATED 2015-05-07 US disclosed
US-8993968-B2 Materials, method, and apparatus for detecting neutrons and ionizing radiation NANOPTICS, INCORPORATED (US) 2015-03-31 US disclosed
EP-2689270-A2 MATERIALS, METHOD, AND APPARATUS FOR DETECTING NEUTRONS AND IONIZING RADIATION Nanoptics, Incorporated (US) 2014-01-29 EP disclosed
WO-2012135140-A2 MATERIALS, METHOD, AND APPARATUS FOR DETECTING NEUTRONS AND IONIZING RADIATION NANOPTICS, INCORPORATED (US) 2012-10-04 WO disclosed
US-20120241630-A1 MATERIALS, METHOD, AND APPARATUS FOR DETECTING NEUTRONS AND IONIZING RADIATION NANOPTICS, INCORPORATED (US) 2012-09-27 US disclosed
US-6977141-B2 Direct adsorption scintillation assay for measuring enzyme activity and assaying biochemical processes VICURON PHARMACEUTICALS INC. (US) 2005-12-20 US disclosed
US-20020015678-A1 DIRECT ADSORPTION SCINTILLATION ASSAY FOR MEASURING ENZYME ACTIVITY AND ASSAYING BIOCHEMICAL PROCESSES VICURON PHARMACEUTICALS INC. 2002-02-07 US disclosed
US-5466930-A Light source for calibrations of imaging devices FLORIDA STATE UNIVERSITY (US) 1995-11-14 US disclosed