Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | TLR7 | Q9NYK1 | 12/20 | 0.41 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.40 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HRH2 | P25021 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6779064 | 0.89 | TLR8 (0.40) | RAB9ASMN1; SMN2TLR7TLR8NUDT1 | |
| SCHEMBL6772264 | 0.87 | TLR7 (0.45) | SMN1; SMN2TLR7TLR8LMNAKDM4E | |
| SCHEMBL6773630 | 0.87 | TLR8 (0.36) | SMN1; SMN2TLR7TLR8NUDT1HRH4 | |
| SCHEMBL6772921 | 0.85 | TLR7 (0.44) | TLR7TLR8NUDT1ALDH1A1 | |
| SCHEMBL6094697 | 0.85 | TLR7 (0.42) | SMN1; SMN2TLR7TLR8LMNA | |
| SCHEMBL6773179 | 0.84 | TLR7 (0.42) | TLR7TLR8NUDT1 | |
| SCHEMBL6288253 | 0.84 | ALDH1A1 (0.42) | RAB9ASMN1; SMN2LMNAKDM4EALDH1A1 | |
| SCHEMBL6779395 | 0.83 | TLR7 (0.46) | RAB9ASMN1; SMN2TLR7TLR8NUDT1 | |
| SCHEMBL6782472 | 0.82 | FAAH (0.47) | TLR7TLR8NUDT1LMNAALDH1A1 | |
| SCHEMBL6779139 | 0.82 | TLR7 (0.44) | TLR7TLR8NUDT1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6720334-B2 | IMMUNE RESPONSE MODIFIERS; CYTOKINE BIOSYNTHESIS; VIRAL AND NEOPLASTIC DISEASES; 1-(4-(4-AMINO-6,7-DIMETHYL-1H-IMIDAZO (4,5-C)PYRIDIN-1-YL)BUTYL)-3-PHENYLUREA. | 3M INNOVATIVE PROPERTIES COMPANY | 2004-04-13 | — | — | US | claimed |