Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.35 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.35 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14342068 | 0.83 | ALDH1A1 (0.32) | ALDH1A1KDM4EHPGDSOS1 | |
| SCHEMBL5281217 | 0.83 | NCEH1 (0.34) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL6778213 | 0.83 | ALDH1A1 (0.37) | MAPTALDH1A1KDM4EHPGDTSHR | |
| SCHEMBL6784280 | 0.80 | NOTUM (0.40) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| Formic Acid SCHEMBL6779717 | 0.80 | KLK1 (0.33) | ALDH1A1HPGD | |
| Formic Acid SCHEMBL6779721 | 0.80 | KLK1 (0.33) | ALDH1A1HPGD | |
| SCHEMBL6777131 | 0.77 | CYP46A1 (0.39) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL6774260 | 0.75 | PDK2 (0.41) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL27567996 | 0.75 | ABL1 (0.41) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL6775145 | 0.75 | CYP46A1 (0.41) | MAPTMEN1KMT2AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6730697-B2 | FOR USE AS ANTIARRYTHMIC MEDICAMENTS WITH A CARDIOPROTECTIVE COMPONENT FOR PROPHYLAXIS OF AN INFARCTION AND THERAPY OF INFARCTION, AND FOR TREATMENT OF ANGINA PECTORIS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2004-05-04 | — | — | US | disclosed |