Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 4/20 | 0.41 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.40 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.36 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | APLNR | P35414 | 4/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6784437 | 0.91 | TLR7 (0.41) | TLR7TLR8KDM4EKMT2AMAPT | |
| SCHEMBL6784344 | 0.88 | TLR7 (0.40) | TLR7TLR8ALDH1A1 | |
| SCHEMBL6778433 | 0.88 | TLR7 (0.47) | TLR7TLR8KDM4EMAPTPKM | |
| SCHEMBL6780382 | 0.86 | TLR7 (0.44) | TLR7TLR8GLO1SLC40A1KDM4E | |
| SCHEMBL6779031 | 0.86 | TLR7 (0.42) | TLR7ALDH1A1 | |
| SCHEMBL6778739 | 0.85 | TLR7 (0.40) | TLR7TLR8GLO1SLC40A1KDM4E | |
| SCHEMBL6774751 | 0.84 | TLR7 (0.43) | TLR7TLR8PKMALDH1A1 | |
| SCHEMBL6779968 | 0.84 | MCHR1 (0.47) | TLR7TLR8 | |
| SCHEMBL6783864 | 0.83 | TLR7 (0.45) | TLR7TLR8ALDH1A1 | |
| SCHEMBL6782531 | 0.83 | CCR3 (0.42) | TLR7TLR8RXFP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6696465-B2 | INDUCING BIOSYNTHESIS OF CYTOKINES; VIRAL AND NEOPLASTIC DISEASES | 3M INNOVATIVE PROPERTIES COMPANY | 2004-02-24 | — | — | US | claimed |