Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 6/20 | 0.39 |
| ▸ | HTR7 | P34969 | 2/20 | 0.37 |
| ▸ | TLR8 | Q9NR97 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | BRAF | P15056 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.33 |
| ▸ | MMP7 | P09237 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6774751 | 0.90 | TLR7 (0.43) | TLR7TLR8ALDH1A1SMN1; SMN2GAA | |
| SCHEMBL6778433 | 0.89 | TLR7 (0.47) | TLR7HTR7TLR8ALDH1A1LMNA | |
| SCHEMBL6775204 | 0.89 | ALDH1A1 (0.45) | TLR7HTR7ALDH1A1SMN1; SMN2 | |
| SCHEMBL6783864 | 0.88 | TLR7 (0.45) | TLR7TLR8ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL6784437 | 0.87 | TLR7 (0.41) | TLR7TLR8ALDH1A1HPGDGAA | |
| SCHEMBL6779031 | 0.85 | TLR7 (0.42) | TLR7HTR7ALDH1A1 | |
| SCHEMBL6775234 | 0.85 | TLR7 (0.44) | TLR7TLR8NUDT1 | |
| SCHEMBL6779472 | 0.85 | HTR7 (0.40) | TLR7HTR7TLR8SMN1; SMN2GAA | |
| SCHEMBL6784344 | 0.85 | TLR7 (0.40) | TLR7HTR7TLR8ALDH1A1SMN1; SMN2 | |
| SCHEMBL6778425 | 0.84 | TLR7 (0.43) | TLR7TLR8NUDT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6696465-B2 | INDUCING BIOSYNTHESIS OF CYTOKINES; VIRAL AND NEOPLASTIC DISEASES | 3M INNOVATIVE PROPERTIES COMPANY | 2004-02-24 | — | — | US | claimed |