Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 8/20 | 0.39 |
| ▸ | CCR4 | P51679 | 3/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 6/20 | 0.35 |
| ▸ | CCR5 | P51681 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.33 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6778162 | 0.86 | TLR7 (0.41) | TSHRALDH1A1TLR7TLR8MAPT | |
| SCHEMBL6778425 | 0.84 | TLR7 (0.43) | TLR7TLR8 | |
| SCHEMBL6778433 | 0.84 | TLR7 (0.47) | TSHRSMN1; SMN2ALDH1A1TLR7TLR8 | |
| SCHEMBL6285401 | 0.84 | TLR7 (0.52) | TLR7TLR8 | |
| SCHEMBL6774751 | 0.83 | TLR7 (0.43) | SMN1; SMN2ALDH1A1TLR7TLR8 | |
| SCHEMBL6779793 | 0.83 | TLR7 (0.41) | KMT2AMEN1SMN1; SMN2ALDH1A1TLR7 | |
| SCHEMBL6778051 | 0.82 | TLR7 (0.46) | ALDH1A1TLR7TLR8 | |
| SCHEMBL6775204 | 0.82 | ALDH1A1 (0.45) | KMT2AMEN1SMN1; SMN2ALDH1A1TLR7 | |
| SCHEMBL6774225 | 0.82 | KMT2A (0.40) | KMT2AMEN1ALDH1A1TLR7TLR8 | |
| SCHEMBL6778097 | 0.82 | TLR7 (0.38) | TLR7TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6696465-B2 | INDUCING BIOSYNTHESIS OF CYTOKINES; VIRAL AND NEOPLASTIC DISEASES | 3M INNOVATIVE PROPERTIES COMPANY | 2004-02-24 | — | — | US | claimed |