Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6772471 | 0.94 | HPGD (0.46) | HPGDMEN1KMT2ATLR7LMNA | |
| SCHEMBL6773093 | 0.90 | KMT2A (0.51) | HPGDMEN1KMT2ATLR7MAPT | |
| SCHEMBL6773831 | 0.85 | TLR7 (0.40) | HPGDHTTMEN1KMT2ATLR7 | |
| SCHEMBL6774292 | 0.84 | ALDH1A1 (0.47) | HPGDMEN1KMT2ATLR7MAPT | |
| SCHEMBL6774657 | 0.83 | MAPT (0.49) | HPGDMEN1KMT2ATLR7LMNA | |
| SCHEMBL8120767 | 0.82 | TLR7 (0.52) | MEN1KMT2ATLR7LMNAMAPT | |
| SCHEMBL6768462 | 0.82 | TLR7 (0.38) | KMT2ATLR7SMN1; SMN2 | |
| SCHEMBL6776784 | 0.81 | ALDH1A1 (0.48) | HPGDHTTMEN1KMT2ATLR7 | |
| SCHEMBL6774879 | 0.81 | TLR7 (0.48) | HPGDTLR7LMNAKDM4EGAA | |
| SCHEMBL6781809 | 0.80 | POLB (0.42) | HPGDMEN1KMT2ATLR7KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6720333-B2 | IMMUNE RESPONSE MODIFIERS; CYTOKINE BIOSYNTHESIS; VIRAL AND NEOPLASTIC DISEASES; N-(4-(4-AMINO-6,7-DIMETHYL-1H-IMIDAZO (4,5-C)PYRIDIN-1-YL)BUTYL)BENZAMIDE | 3M INNOVATIVE PROPERTIES COMPANY | 2004-04-13 | — | — | US | claimed |