Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | PKM | P14618 | 5/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 5/20 | 0.46 |
| ▸ | GAA | P10253 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | GLA | P06280 | 3/20 | 0.43 |
| ▸ | TLR7 | Q9NYK1 | 4/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6781809 | 0.92 | POLB (0.42) | MAPTALDH1A1PKMSMN1; SMN2NPC1 | |
| SCHEMBL6782569 | 0.90 | SMN1; SMN2 (0.44) | MAPTALDH1A1PKMSMN1; SMN2NPC1 | |
| SCHEMBL6773253 | 0.89 | GAA (0.41) | MAPTALDH1A1PKMPOLBGAA | |
| SCHEMBL6768482 | 0.89 | IDO1 (0.47) | MAPTALDH1A1PKMSMN1; SMN2NPC1 | |
| SCHEMBL6768729 | 0.88 | TLR7 (0.47) | MAPTALDH1A1PKMSMN1; SMN2NPC1 | |
| SCHEMBL6771355 | 0.87 | POLB (0.47) | MAPTALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL6773364 | 0.87 | RXFP1 (0.43) | MAPTALDH1A1PKMNPC1POLB | |
| SCHEMBL6779087 | 0.86 | NOS3 (0.48) | ALDH1A1PKMRAB9AMEN1KMT2A | |
| SCHEMBL6773842 | 0.86 | SMN1; SMN2 (0.50) | MAPTALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL6773218 | 0.85 | MCHR1 (0.47) | MAPTALDH1A1PKMPOLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6720333-B2 | IMMUNE RESPONSE MODIFIERS; CYTOKINE BIOSYNTHESIS; VIRAL AND NEOPLASTIC DISEASES; N-(4-(4-AMINO-6,7-DIMETHYL-1H-IMIDAZO (4,5-C)PYRIDIN-1-YL)BUTYL)BENZAMIDE | 3M INNOVATIVE PROPERTIES COMPANY | 2004-04-13 | — | — | US | claimed |