Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6774292 | 0.94 | ALDH1A1 (0.47) | KMT2AMEN1MAPTTLR7HSD17B10 | |
| SCHEMBL6778680 | 0.90 | HPGD (0.43) | KMT2AMEN1MAPTTLR7ALDH1A1 | |
| SCHEMBL6774657 | 0.85 | MAPT (0.49) | KMT2AMEN1MAPTTLR7ALDH1A1 | |
| SCHEMBL6779679 | 0.84 | HPGD (0.46) | KMT2AMEN1HSD17B10ALDH1A1HPGD | |
| SCHEMBL6776784 | 0.83 | ALDH1A1 (0.48) | KMT2AMEN1TLR7HSD17B10ALDH1A1 | |
| SCHEMBL6279157 | 0.81 | TLR7 (0.37) | KMT2AMEN1MAPTTLR7ALDH1A1 | |
| SCHEMBL6781809 | 0.81 | POLB (0.42) | KMT2AMEN1MAPTTLR7ALDH1A1 | |
| SCHEMBL6779590 | 0.81 | MAPKAPK2 (0.43) | KMT2AMEN1MAPTTLR7ALDH1A1 | |
| SCHEMBL6110335 | 0.81 | KDM4E (0.39) | TLR7ALDH1A1GAAHPGDCNR1 | |
| SCHEMBL6771821 | 0.80 | TLR7 (0.47) | KMT2AMEN1MAPTTLR7ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6720333-B2 | IMMUNE RESPONSE MODIFIERS; CYTOKINE BIOSYNTHESIS; VIRAL AND NEOPLASTIC DISEASES; N-(4-(4-AMINO-6,7-DIMETHYL-1H-IMIDAZO (4,5-C)PYRIDIN-1-YL)BUTYL)BENZAMIDE | 3M INNOVATIVE PROPERTIES COMPANY | 2004-04-13 | — | — | US | claimed |