SCHEMBL6778754

SCHEMBL6778754

C[CH]C(=O)N1CCNCC1C(C)C

nearest known ligand 0.42

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 1/20 0.42
DPP7 Q9UHL4 1/20 0.42
USP19 O94966 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
SMYD3 Q9H7B4 1/20 0.30
PIK3CD O00329 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24820026 0.85 DPP4 (0.41) DPP4DPP7USP19SMYD3
SCHEMBL24368972 0.81 DPP4 (0.44) DPP4DPP7USP19TDP1SMYD3
SCHEMBL2636048 0.81 DPP4 (0.44) DPP4DPP7USP19TDP1SMYD3
SCHEMBL24368970 0.81 DPP4 (0.44) DPP4DPP7USP19TDP1SMYD3
SCHEMBL14843725 0.81 DPP4 (0.44) DPP4DPP7USP19TDP1SMYD3
SCHEMBL22034571 0.81 DPP4 (0.44) DPP4DPP7USP19TDP1SMYD3
SCHEMBL24369514 0.79 DPP4 (0.46) DPP4DPP7USP19TDP1SMYD3
SCHEMBL787532 0.79 DPP4 (0.46) DPP4DPP7USP19SMYD3PIK3CD
SCHEMBL24369511 0.79 DPP4 (0.46) DPP4DPP7USP19TDP1SMYD3
Hydrochloric Acid SCHEMBL15709523 0.78 DPP4 (0.45) DPP4DPP7USP19SMYD3PIK3CD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6825191-B2 ANTICOAGULANT AJINOMOTO CO., INC. (JP) 2004-11-30 US claimed
US-20030186969-A1 Benzodiazepine derivatives AJINOMOTO CO. INC (JP) 2003-10-02 US claimed
EP-1329450-A1 BENZODIAZEPINE DERIVATIVE Ajinomoto Co., Inc. (JP) 2003-07-23 EP claimed
US-6825191-B2 ANTICOAGULANT AJINOMOTO CO., INC. (JP) 2004-11-30 US disclosed
US-20030186969-A1 Benzodiazepine derivatives AJINOMOTO CO. INC (JP) 2003-10-02 US disclosed
EP-1329450-A1 BENZODIAZEPINE DERIVATIVE Ajinomoto Co., Inc. (JP) 2003-07-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030186969-A1 Benzodiazepine derivatives GABRA1, F11, GABRA4 DPP4 1638/4885DPP7 2630/4885USP19 3245/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.