Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 5/20 | 0.39 |
| ▸ | DRD3 | P35462 | 3/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | STS | P08842 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5996688 | 0.88 | DRD2 (0.46) | DRD2DRD3CHRNB2CHRNA4CHRNA7 | |
| Hydrochloric Acid SCHEMBL7860155 | 0.87 | DRD2 (0.46) | DRD2DRD3STSS1PR5CA12 | |
| SCHEMBL5997736 | 0.86 | CHRNB2 (0.52) | DRD2DRD3CHRNB2CHRNA4CHRNB4 | |
| Hydrochloric Acid SCHEMBL5995210 | 0.85 | CHRNB2 (0.51) | DRD2DRD3CHRNB2CHRNA4CHRNB4 | |
| SCHEMBL5997232 | 0.84 | CHRNB2 (0.56) | FAAHDRD2DRD3CHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL6814278 | 0.83 | CHRNB2 (0.55) | FAAHDRD2DRD3CHRNB2CHRNA4 | |
| SCHEMBL5996730 | 0.81 | CHRNB2 (0.55) | DRD2DRD3CHRNB2CHRNA4CHRNB4 | |
| SCHEMBL6777528 | 0.79 | SLC6A2 (0.43) | DRD2DRD3MAPTKDM4ES1PR5 | |
| Hydrochloric Acid SCHEMBL6773315 | 0.78 | SLC6A2 (0.43) | DRD2DRD3MAPTKDM4ES1PR5 | |
| SCHEMBL5996694 | 0.78 | CHRNB2 (0.49) | DRD2DRD3CHRNB2CHRNA4CHRNB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6706702-B2 | FOR THERAPY OF NEUROLOGICAL AND PSYCHOLOGICAL DISORDERS | PFIZER INC. | 2004-03-16 | — | — | US | disclosed |
| US-20030008890-A1 | Aryl fused azapolycyclic compounds | COE JOTHAM WADSWORTH (US) | 2003-01-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030008890-A1 | Aryl fused azapolycyclic compounds | GRIN2C, GRIN2A, NR3C1 | FAAH 1220/4885DRD2 75/4885DRD3 78/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.