SCHEMBL677887

SCHEMBL677887

CC(Br)c1ccc(C(=O)c2ccccc2)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.56
SRD5A2 P31213 1/20 0.54
MEN1 O00255 1/20 0.53
KMT2A Q03164 1/20 0.53
HPGD P15428 5/20 0.51
SMN1; SMN2 Q16637 4/20 0.51
PTGS1 P23219 3/20 0.51
PTGS2 P35354 3/20 0.51
RAB9A P51151 3/20 0.51
MAPT P10636 2/20 0.51
CXCR1 P25024 2/20 0.51
CXCR2 P25025 2/20 0.51
ELANE P08246 2/20 0.51
LMNA P02545 2/20 0.51
HTT P42858 1/20 0.51
NPSR1 Q6W5P4 1/20 0.51
RECQL P46063 1/20 0.51
KDM4E B2RXH2 1/20 0.51
CYP3A4 P08684 1/20 0.51
MAPK1 P28482 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9442717 0.94 MAPT (0.56) ALDH1A1SRD5A2MEN1KMT2AHPGD
SCHEMBL4541365 0.83 ALDH1A1 (0.61) ALDH1A1SRD5A2MEN1KMT2AHPGD
SCHEMBL50522 0.83 ALDH1A1 (0.61) ALDH1A1SRD5A2MEN1KMT2AHPGD
SCHEMBL10022962 0.83 ALDH1A1 (0.61) ALDH1A1SRD5A2MEN1KMT2AHPGD
SCHEMBL13653041 0.83 PTGS1 (0.70) ALDH1A1MEN1KMT2AHPGDSMN1; SMN2
SCHEMBL9636442 0.83 PTGS1 (0.70) ALDH1A1MEN1KMT2AHPGDSMN1; SMN2
SCHEMBL8008483 0.82 MAPK1 (0.53) ALDH1A1SRD5A2MEN1KMT2AHPGD
SCHEMBL28587552 0.82 ALDH1A1 (0.58) ALDH1A1SRD5A2MEN1KMT2AHPGD
SCHEMBL28276679 0.82 ALDH1A1 (0.58) ALDH1A1SRD5A2MEN1KMT2AHPGD
SCHEMBL508553 0.81 TSHR (0.55) ALDH1A1SRD5A2KMT2AHPGDSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103221436-B The approach of polyacrylic ester COLOPLAST A/S (DK) 2015-09-09 CN disclosed
CN-104804111-A Synthetic method and application of Michler's ketone photo-initiator UNIV JIANGXI NORMAL SCI & TECH 2015-07-29 CN disclosed
CN-103201295-B Novel polymeric photoinitiators COLOPLAST AS 2015-04-29 CN disclosed
CN-103058902-B Photoactive reversible addition-breakage chain transfer reagent and preparation and application thereof UNIV JIANGXI NORMAL SCI & TECH 2014-08-13 CN disclosed
CN-103221436-A New routes to polyacrylates COLOPLAST AS 2013-07-24 CN disclosed
CN-103201295-A Novel polymeric photoinitiators COLOPLAST AS 2013-07-10 CN disclosed
CN-103058902-A Photoactive reversible addition-breakage chain transfer reagent and preparation and application thereof UNIV JIANGXI NORMAL SCI & TECH 2013-04-24 CN disclosed
EP-1619211-B1 PROCESS FOR PRODUCTION OF LIVING-RADICAL POLYMERS AND POLYMERS OTSUKA CHEMICAL CO LTD (JP) 2012-10-17 EP disclosed
US-20110275774-A1 ORGANOANTIMONY COMPOUND, PROCESS FOR PREPARING SAME, LIVING RADICAL POLYMERIZATION INITIATOR, PROCESS FOR PRODUCING POLYMER WITH USE OF SAME, AND THE POLYMER YAMAGO SHIGERU 2011-11-10 US disclosed
EP-1595894-B1 PROCESS FOR THE PRODUCTION OF LIVING RADICAL POLYMERS OTSUKA CHEMICAL CO LTD (JP) 2011-10-12 EP disclosed
US-20060167199-A1 Process for produciton of living radical polymers and polymers OTSUKA CHEMICAL CO., LTD. (JP) 2006-07-27 US disclosed
US-20060135711-A1 Process for the production of living radical polymers and polymers OTSUKA CHEMICAL CO., LTD. (JP) 2006-06-22 US disclosed
EP-1619211-A1 PROCESS FOR PRODUCTION OF LIVING-RADICAL POLYMERS AND POLYMERS OTSUKA CHEMICAL COMPANY, LIMITED (JP) 2006-01-25 EP disclosed
EP-1595894-A1 PROCESS FOR THE PRODUCTION OF LIVING RADICAL POLYMERS AND POLYMERS OTSUKA CHEMICAL COMPANY, LIMITED (JP) 2005-11-16 EP disclosed
US-20050245714-A1 Organic tellurium compound, process for producing the same, living radical polymerization initiator, process for producing polymer with the same, and polymer OTSUKA CHEMICAL CO., LTD. (JP) 2005-11-03 US disclosed
EP-1541550-A1 ORGANIC TELLURIUM COMPOUND, PROCESS FOR PRODUCING THE SAME, LIVING RADICAL POLYMERIZATION INITIATOR, PROCESS FOR PRODUCING POLYMER WITH THE SAME, AND POLYMER Otsuka Chemical Co., Ltd. (JP) 2005-06-15 EP disclosed
EP-1541592-A1 PROCESS FOR PRODUCTION OF LIVING RADICAL POLYMERS AND POLYMERS OTSUKA CHEMICAL COMPANY, LIMITED (JP) 2005-06-15 EP disclosed
CN-1582279-A Peroxisome-activated receptor agonists LILLY CO ELI (US) 2005-02-16 CN disclosed
EP-0422236-B1 PRODUCTION OF ALKENYLBENZOPHENONE NIPPON PETROCHEMICALS CO LTD (JP) 1995-06-14 EP disclosed
EP-0422236-A1 PRODUCTION OF ALKENYLBENZOPHENONE NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1991-04-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050245714-A1 Organic tellurium compound, process for producing the same, living radical polymerization initiator, process for producing polymer with the same, and polymer ODC1, TERB1, TTI1 ALDH1A1 1201/4885SRD5A2 2486/4885MEN1 806/4885
US-20060135711-A1 Process for the production of living radical polymers and polymers CBR3, CBR1, CCNT1 ALDH1A1 483/4885SRD5A2 2573/4885MEN1 1560/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.