Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.55 |
| ▸ | HPGD | P15428 | 4/20 | 0.55 |
| ▸ | RAB9A | P51151 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.55 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.55 |
| ▸ | ELANE | P08246 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.55 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11988241 | 0.96 | ALDH1A1 (0.55) | ALDH1A1SRD5A2SMN1; SMN2HPGDRAB9A | |
| SCHEMBL50522 | 0.87 | ALDH1A1 (0.61) | ALDH1A1SRD5A2SMN1; SMN2HPGDRAB9A | |
| SCHEMBL9148045 | 0.87 | SMN1; SMN2 (0.47) | ALDH1A1SRD5A2SMN1; SMN2HPGDRAB9A | |
| SCHEMBL28587552 | 0.85 | ALDH1A1 (0.58) | ALDH1A1SRD5A2SMN1; SMN2HPGDRAB9A | |
| SCHEMBL10022965 | 0.85 | ELANE (0.62) | ALDH1A1MAPTELANETDP1L3MBTL1 | |
| SCHEMBL19788333 | 0.84 | PTGS1 (0.72) | ALDH1A1SMN1; SMN2HPGDMAPTPTGS1 | |
| SCHEMBL677887 | 0.83 | ALDH1A1 (0.56) | ALDH1A1SRD5A2SMN1; SMN2HPGDRAB9A | |
| SCHEMBL21276570 | 0.83 | ALDH1A1 (0.56) | ALDH1A1SRD5A2SMN1; SMN2HPGDRAB9A | |
| SCHEMBL11141744 | 0.83 | ALDH1A1 (0.56) | ALDH1A1SRD5A2SMN1; SMN2HPGDRAB9A | |
| SCHEMBL7704968 | 0.83 | PTGS2 (0.71) | ALDH1A1SRD5A2SMN1; SMN2HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8932797-B2 | Photoacid generators | DOW GLOBAL TECHNOLOGIES LLC (US) | 2015-01-13 | — | — | US | disclosed |
| US-8907122-B2 | Method of preparing photoacid generating monomer | ROHM AND HAAS ELECTRONIC MATERIAL LLC (US) | 2014-12-09 | — | — | US | disclosed |
| US-8716518-B2 | Photoacid generating monomer and precursor thereof | ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) | 2014-05-06 | — | — | US | disclosed |
| US-20120172619-A1 | METHOD OF PREPARING PHOTOACID GENERATING MONOMER | ROHM AND HAAS ELECTRONIC MATERIALS LLC | 2012-07-05 | — | — | US | disclosed |
| US-20120172555-A1 | PHOTOACID GENERATING MONOMER AND PRECURSOR THEREOF | DOW GLOBAL TECHNOLOGIES LLC | 2012-07-05 | — | — | US | disclosed |
| US-20120141939-A1 | PHOTOACID GENERATORS | U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT | 2012-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120141939-A1 | PHOTOACID GENERATORS | F10, GNG2, H1-0 | ALDH1A1 1308/4885SRD5A2 3466/4885SMN1; SMN2 4311/4885 |
| US-20120172555-A1 | PHOTOACID GENERATING MONOMER AND PRECURSOR THEREOF | SULT1A1, SULT1E1, SULT2A1 | ALDH1A1 396/4885SRD5A2 795/4885SMN1; SMN2 4149/4885 |
| US-20120172619-A1 | METHOD OF PREPARING PHOTOACID GENERATING MONOMER | POLL, SULT1A1, SULT1E1 | ALDH1A1 277/4885SRD5A2 1495/4885SMN1; SMN2 2961/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.