Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 6/20 | 0.43 |
| ▸ | DRD3 | P35462 | 6/20 | 0.43 |
| ▸ | DRD4 | P21917 | 3/20 | 0.43 |
| ▸ | FAAH | O00519 | 3/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | F10 | P00742 | 2/20 | 0.42 |
| ▸ | F2 | P00734 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.42 |
| ▸ | F7 | P08709 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6780268 | 0.95 | F10 (0.46) | MEN1POLBKMT2ADRD2DRD3 | |
| SCHEMBL6779801 | 0.94 | F10 (0.43) | MEN1POLBKMT2ADRD2DRD3 | |
| SCHEMBL6780280 | 0.91 | LMNA (0.47) | MEN1POLBKMT2ATSHRF10 | |
| SCHEMBL6778302 | 0.88 | POLB (0.45) | MEN1POLBKMT2ADRD2DRD4 | |
| SCHEMBL6785087 | 0.88 | MAPT (0.46) | MEN1POLBKMT2AF10F2 | |
| SCHEMBL6779135 | 0.88 | TSHR (0.44) | MEN1POLBKMT2ADRD2DRD3 | |
| SCHEMBL6777979 | 0.87 | KDM4E (0.44) | MEN1POLBKMT2ADRD2DRD3 | |
| SCHEMBL6779349 | 0.87 | TSHR (0.48) | MEN1POLBKMT2ADRD2DRD3 | |
| Hydrochloric Acid SCHEMBL6366397 | 0.86 | TSHR (0.48) | MEN1KMT2ADRD2DRD3DRD4 | |
| SCHEMBL6774764 | 0.86 | F2 (0.55) | MEN1POLBKMT2ATSHRF10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6794507-B2 | Compounds that inhibit factor Xa activity | MORPHOCHEM AG (DE) | 2004-09-21 | — | — | US | disclosed |
| US-20030153510-A1 | Novel compounds inhibiting factor xa activity | CAPPI MICHAEL W (DE) | 2003-08-14 | — | — | US | disclosed |
| EP-1311473-A2 | NOVEL COMPOUNDS INHIBITING FACTOR XA ACTIVITY | Morphochem AG (DE) | 2003-05-21 | — | — | EP | disclosed |
| WO-2002016312-A2 | NOVEL COMPOUNDS INHIBITING FACTOR XA ACTIVITY | MORPHOCHEM AG (DE) | 2002-02-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030153510-A1 | Novel compounds inhibiting factor xa activity | SERPINC1, F11, TFPI | MEN1 592/4885POLB 4322/4885KMT2A 4159/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.