SCHEMBL6779197

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL31314518	1.00	HTT (0.62)	HTTCYP3A4LCKFYNKDM4E
	SCHEMBL2848241	0.90	HTT (0.50)	HTTCYP3A4KDM4ERAB9ALMNA
	SCHEMBL1498783	0.86	HTT (0.61)	HTTCYP3A4KDM4ERAB9ALMNA
	SCHEMBL13927530	0.86	HTT (0.47)	HTTCYP3A4KDM4ERAB9ALMNA
	SCHEMBL22222472	0.85	HTT (0.46)	HTTCYP3A4KDM4ERAB9ALMNA
	SCHEMBL9958729	0.85	HTT (0.46)	HTTCYP3A4LCKFYNRAB9A
	SCHEMBL6719734	0.85	NPC1 (0.51)	HTTCYP3A4KDM4ERAB9ALMNA
	SCHEMBL7891214	0.85	HTT (0.50)	HTTCYP3A4LCKFYNRAB9A
	SCHEMBL1766160	0.83	LCK (0.60)	HTTCYP3A4LCKFYNKDM4E
	SCHEMBL20780495	0.82	HTT (0.43)	HTTCYP3A4RAB9ALMNAMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.