Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | PPOX | P50336 | 1/20 | 0.41 |
| ▸ | PYGL | P06737 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28052752 | 0.87 | NPC1 (0.49) | NPC1RAB9AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL6742902 | 0.86 | PYGL (0.49) | NPC1RAB9AMAPTHTTSMN1; SMN2 | |
| SCHEMBL31314518 | 0.85 | HTT (0.62) | RAB9AHTTKMT2AKDM4ELMNA | |
| SCHEMBL6779197 | 0.85 | HTT (0.62) | RAB9AHTTKMT2AKDM4ELMNA | |
| SCHEMBL8067926 | 0.84 | GAA (0.53) | NPC1RAB9AMAPTHTTSMN1; SMN2 | |
| SCHEMBL3347725 | 0.84 | NPC1 (0.47) | NPC1RAB9AMAPTHTTSMN1; SMN2 | |
| SCHEMBL6742081 | 0.83 | HTT (0.55) | NPC1RAB9AMAPTHTTSMN1; SMN2 | |
| SCHEMBL6284961 | 0.83 | RAB9A (0.46) | NPC1RAB9AMAPTHTTSMN1; SMN2 | |
| SCHEMBL7482306 | 0.83 | RORC (0.48) | NPC1RAB9AMAPTSMN1; SMN2HPGD | |
| SCHEMBL7695094 | 0.81 | HMGCR (0.54) | NPC1RAB9AMAPTSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101270117-B | Herbicide and preparation thereof | UNIV DALIAN TECH | 2012-02-29 | — | — | CN | claimed |
| CN-101279972-B | Benzoxazole herbicides and preparation thereof | UNIV DALIAN TECH | 2011-02-02 | — | — | CN | claimed |
| CN-101870677-A | 5-arylmethoxy phenyl pyrazole compound and preparation method thereof | UNIV DALIAN TECH | 2010-10-27 | — | — | CN | claimed |
| CN-101279972-A | Benzoxazole herbicides and preparation thereof | UNIV DALIAN TECH (CN) | 2008-10-08 | — | — | CN | claimed |
| CN-101270117-A | Herbicide and preparation thereof | UNIV DALIAN TECH (CN) | 2008-09-24 | — | — | CN | claimed |
| CN-101270117-B | Herbicide and preparation thereof | UNIV DALIAN TECH | 2012-02-29 | — | — | CN | disclosed |
| CN-101279972-B | Benzoxazole herbicides and preparation thereof | UNIV DALIAN TECH | 2011-02-02 | — | — | CN | disclosed |
| CN-101870677-A | 5-arylmethoxy phenyl pyrazole compound and preparation method thereof | UNIV DALIAN TECH | 2010-10-27 | — | — | CN | disclosed |
| CN-101279972-A | Benzoxazole herbicides and preparation thereof | UNIV DALIAN TECH (CN) | 2008-10-08 | — | — | CN | disclosed |
| CN-101270117-A | Herbicide and preparation thereof | UNIV DALIAN TECH (CN) | 2008-09-24 | — | — | CN | disclosed |
| EP-0791571-B1 | Benzoyl derivatives | BAYER CROPSCIENCE AG (DE) | 2004-06-16 | — | — | EP | disclosed |
| US-20040092402-A1 | Pyrimidine derivatives and herbicides containing the same | SUMITOMO CHEMICAL TAKEDA AGRO COMPANY, LIMITED (JP) | 2004-05-13 | — | — | US | disclosed |
| CN-1090845-A | Process for preparing substituted aryl-halogenoalkyl pyrazoles | MONSANTO CO (US) | 1994-08-17 | — | — | CN | disclosed |
| US-5281571-A | Herbicidal benzoxazinone- and benzothiazinone-substituted pyrazoles | MONSANTO COMPANY (US) | 1994-01-25 | — | — | US | disclosed |
| EP-0553307-A1 | HERBICIDAL SUBSTITUTED ARYL-HALOALKYLPYRAZOLES | MONSANTO COMPANY (US) | 1993-08-04 | — | — | EP | disclosed |
| EP-0542872-A1 | HERBICIDAL SUBSTITUTED ARYL ALKYLSULFONYL PYRAZOLES | MONSANTO COMPANY (US) | 1993-05-26 | — | — | EP | disclosed |
| CN-1061777-A | Substituted aryl-haloalkyl-pyrazoles as herbicides | MONSANTO CO (US) | 1992-06-10 | — | — | CN | disclosed |
| CN-1061221-A | The aryl alkylsulfonyl pyrazoles of the replacement of weeding | MONSANTO CO (US) | 1992-05-20 | — | — | CN | disclosed |
| WO-1992006962-A1 | HERBICIDAL SUBSTITUTED ARYL-HALOALKYLPYRAZOLES | MONSANTO COMPANY (US) | 1992-04-30 | — | — | WO | disclosed |
| WO-1992002509-A1 | HERBICIDAL SUBSTITUTED ARYL ALKYLSULFONYL PYRAZOLES | MONSANTO COMPANY (US) | 1992-02-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040092402-A1 | Pyrimidine derivatives and herbicides containing the same | DDX41, CBR3, DPYD | NPC1 4456/4885RAB9A 3424/4885MAPT 4526/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.