Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 3/20 | 0.42 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MGAM | O43451 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8925795 | 0.84 | CYP4F2 (0.46) | CYP4F2CYP4A11ALDH1A1ABCB11CYP1A2 | |
| SCHEMBL5613576 | 0.82 | ALDH1A1 (0.39) | ALDH1A1TSHRLMNAHSD17B10 | |
| SCHEMBL28180996 | 0.82 | CYP4F2 (0.44) | CYP4F2CYP4A11ALDH1A1ABCB11CYP1A2 | |
| SCHEMBL29328728 | 0.82 | ALOX15 (0.41) | CYP4F2CYP4A11ALDH1A1ABCB11CYP1A2 | |
| SCHEMBL29324449 | 0.82 | CYP4F2 (0.40) | CYP4F2CYP4A11ALDH1A1ABCB11CYP1A2 | |
| SCHEMBL28204938 | 0.80 | ALDH1A1 (0.36) | ALDH1A1SOAT1 | |
| SCHEMBL4300603 | 0.80 | ALDH1A1 (0.46) | CYP4F2CYP4A11ALDH1A1ABCB11CYP1A2 | |
| SCHEMBL513322 | 0.80 | — | — | |
| SCHEMBL7107426 | 0.80 | — | — | |
| SCHEMBL862581 | 0.79 | ALDH1A1 (0.48) | ALDH1A1CYP1A2CYP3A4TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115667369-A | Composition for optical material | 三菱瓦斯化学株式会社 | 2023-01-31 | — | — | CN | claimed |
| CN-113501757-B | Preparation and refining method of high-purity diethyl chloropropionate | 长沙创新药物工业技术研究院有限公司 | 2022-12-13 | — | — | CN | claimed |
| CN-113501757-A | Preparation and refining method of high-purity diethyl chloropropionate | 湖南华腾制药有限公司 | 2021-10-15 | — | — | CN | claimed |
| CN-111440123-A | Synthetic method of 4,5, 6-trichloropyrimidine | 南京普锐达医药科技有限公司 | 2020-07-24 | — | — | CN | claimed |
| CN-115916774-A | Process for the preparation of fluoxastrobin and intermediates thereof | UPL有限公司 | 2023-04-04 | — | — | CN | disclosed |
| CN-115916774-A | Process for the preparation of fluoxastrobin and intermediates thereof | UPL有限公司 | 2023-04-04 | — | — | CN | disclosed |
| CN-115667369-A | Composition for optical material | 三菱瓦斯化学株式会社 | 2023-01-31 | — | — | CN | disclosed |
| CN-115667369-A | Composition for optical material | 三菱瓦斯化学株式会社 | 2023-01-31 | — | — | CN | disclosed |
| CN-115490641-A | Synthesis method of 2-methyl-4, 5, 6-trichloropyrimidine | 大连大学 | 2022-12-20 | — | — | CN | disclosed |
| CN-113501757-B | Preparation and refining method of high-purity diethyl chloropropionate | 长沙创新药物工业技术研究院有限公司 | 2022-12-13 | — | — | CN | disclosed |
| CN-113501757-B | Preparation and refining method of high-purity diethyl chloropropionate | 长沙创新药物工业技术研究院有限公司 | 2022-12-13 | — | — | CN | disclosed |
| CN-113501757-B | Preparation and refining method of high-purity diethyl chloropropionate | 长沙创新药物工业技术研究院有限公司 | 2022-12-13 | — | — | CN | disclosed |
| EP-0843667-B1 | SUBSTITUTED PHENYLURACILS | BAYER AG (DE) | 2001-10-17 | — | — | EP | disclosed |
| US-6251828-B1 | HERBICIDE FOR TOTAL CONTROL OF WEEDS | BAYER AKTIENGESELLSCHAFT (DE) | 2001-06-26 | — | — | US | disclosed |
| US-20010003732-A1 | 1-(4-cyano-2-fluoro-5-(2-chloro-2-methoxycarbonylethyl) -phenyl)-3,6-dihydro-2,6-dioxo-3-methyl-4-trifluoromethyl-1-(2H)-pyrimidine, for example; use as herbicides; chemical intermediates and method of synthesis | ANDREE ROLAND (DE) | 2001-06-14 | — | — | US | disclosed |
| CN-1197455-A | Substituted phenyluracils | BAYER AG (DE) | 1998-10-28 | — | — | CN | disclosed |
| EP-0843667-A1 | SUBSTITUTED PHENYLURACILS | BAYER AG (DE) | 1998-05-27 | — | — | EP | disclosed |
| WO-1997005118-A1 | SUBSTITUTED PHENYLURACILS | BAYER AKTIENGESELLSCHAFT (DE) | 1997-02-13 | — | — | WO | disclosed |
| EP-0317960-A2 | A process to produce silyl ketene acetals | DOW CORNING CORPORATION (US) | 1989-05-31 | — | — | EP | disclosed |
| US-4783543-A | REACTING CARBOXYLIC ESTER WITH ALKALI METAL IN PRESENCE OF EXCESS ORGANOHALOSILANE | DOW CORNING CORPORATION (US) | 1988-11-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010003732-A1 | 1-(4-cyano-2-fluoro-5-(2-chloro-2-methoxycarbonylethyl) -phenyl)-3,6-dihydro-2,6-dioxo-3-methyl-4-trifluoromethyl-1-(2H)-pyrimidine, for example; use as herbicides; chemical intermediates and method of synthesis | DDT, DPYD, DHFR | CYP4F2 32/4885CYP4A11 833/4885ALDH1A1 132/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.