Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 3/20 | 0.40 |
| ▸ | TLR7 | Q9NYK1 | 7/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 6/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.36 |
| ▸ | CCR1 | P32246 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MMP7 | P09237 | 1/20 | 0.34 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | OXTR | P30559 | 1/20 | 0.34 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6776957 | 0.90 | TLR7 (0.42) | TLR7TLR8NUDT1GAAMAPK1 | |
| SCHEMBL6783392 | 0.89 | TLR7 (0.47) | HTR7TLR7TLR8NUDT1GAA | |
| SCHEMBL6774343 | 0.88 | ALDH1A1 (0.44) | HTR7TLR7TLR8HTR1AHTR2A | |
| SCHEMBL6780460 | 0.87 | TLR7 (0.44) | TLR7TLR8NUDT1GAAMAPK1 | |
| SCHEMBL6778238 | 0.87 | TLR7 (0.44) | TLR7TLR8NUDT1GAAMAPK1 | |
| SCHEMBL6783227 | 0.85 | TLR7 (0.39) | HTR7TLR7TLR8NUDT1GAA | |
| SCHEMBL6775218 | 0.85 | POLB (0.42) | HTR7TLR7TLR8HTR1AHTR2A | |
| SCHEMBL6774495 | 0.85 | TLR7 (0.43) | TLR7TLR8NUDT1 | |
| SCHEMBL6783636 | 0.84 | TLR7 (0.39) | HTR7TLR7TLR8HTR2AHTR6 | |
| SCHEMBL6777551 | 0.83 | TLR7 (0.41) | TLR7TLR8NUDT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6696465-B2 | INDUCING BIOSYNTHESIS OF CYTOKINES; VIRAL AND NEOPLASTIC DISEASES | 3M INNOVATIVE PROPERTIES COMPANY | 2004-02-24 | — | — | US | claimed |