Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 14/20 | 0.44 |
| ▸ | TLR8 | Q9NR97 | 8/20 | 0.43 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6783392 | 0.95 | TLR7 (0.47) | TLR7TLR8NUDT1LMNAMAPK1 | |
| SCHEMBL6776957 | 0.91 | TLR7 (0.42) | TLR7TLR8NUDT1MAPK1SMN1; SMN2 | |
| SCHEMBL6775218 | 0.89 | POLB (0.42) | TLR7TLR8LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL6774343 | 0.89 | ALDH1A1 (0.44) | TLR7TLR8LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL6778238 | 0.87 | TLR7 (0.44) | TLR7TLR8NUDT1MAPK1SMN1; SMN2 | |
| SCHEMBL6779472 | 0.87 | HTR7 (0.40) | TLR7TLR8NUDT1MAPK1SMN1; SMN2 | |
| SCHEMBL6774423 | 0.86 | TLR7 (0.41) | TLR7HDAC1HDAC2LMNAMAPK1 | |
| SCHEMBL6783864 | 0.85 | TLR7 (0.45) | TLR7TLR8NUDT1HDAC1HDAC2 | |
| SCHEMBL6783636 | 0.85 | TLR7 (0.39) | TLR7TLR8NUDT1SMN1; SMN2ALDH1A1 | |
| SCHEMBL6777836 | 0.84 | TLR7 (0.43) | TLR7TLR8NUDT1LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6696465-B2 | INDUCING BIOSYNTHESIS OF CYTOKINES; VIRAL AND NEOPLASTIC DISEASES | 3M INNOVATIVE PROPERTIES COMPANY | 2004-02-24 | — | — | US | claimed |