Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | GCG | P01275 | 2/20 | 0.60 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.58 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.58 |
| ▸ | GCGR | P47871 | 2/20 | 0.53 |
| ▸ | CCNE1 | P24864 | 6/20 | 0.49 |
| ▸ | CDK2 | P24941 | 6/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.45 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | DPP4 | P27487 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6779496 | 0.79 | FFAR1 (0.55) | GCGFFAR1FFAR4DPP4HDAC3 | |
| SCHEMBL6778391 | 0.79 | FFAR1 (0.55) | MEN1KMT2AFFAR1FFAR4CCNE1 | |
| SCHEMBL14044097 | 0.79 | FFAR1 (0.66) | MEN1KMT2AGCGFFAR1FFAR4 | |
| SCHEMBL6924151 | 0.79 | FFAR1 (0.58) | KMT2AGCGFFAR1FFAR4GCGR | |
| SCHEMBL11511314 | 0.78 | MEN1 (0.68) | MEN1KMT2AFFAR1CCNE1CDK2 | |
| SCHEMBL28227000 | 0.77 | FFAR1 (0.52) | MEN1KMT2AGCGFFAR1FFAR4 | |
| SCHEMBL14055487 | 0.77 | GCG (1.00) | GCGGCGR | |
| SCHEMBL6237822 | 0.76 | FFAR1 (0.75) | GCGFFAR1FFAR4SMN1; SMN2GAA | |
| SCHEMBL11511026 | 0.76 | CYP2A6 (0.48) | MEN1KMT2AFFAR1FFAR4MAPT | |
| SCHEMBL15497176 | 0.75 | MEN1 (0.64) | MEN1KMT2ACCNE1CDK2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6780883-B2 | ANTICHOLESTEROL AGENTS; CARDIOVASCULAR DISORDERS; ANTILIPEMIC AGENTS; RESTENOSIS; DIETETICS | WARNER-LAMBERT COMPANY | 2004-08-24 | — | — | US | disclosed |
| US-20020156281-A1 | Amide inhibitors of microsomal triglyceride transfer protein | BOOTH RICHARD JOHN (US) | 2002-10-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020156281-A1 | Amide inhibitors of microsomal triglyceride transfer protein | CETP, MTTP, LCAT | MEN1 4612/4885KMT2A 1440/4885GCG 2692/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.