Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.55 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.55 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | KCNA5 | P22460 | 4/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
| ▸ | F2 | P00734 | 2/20 | 0.44 |
| ▸ | DPP4 | P27487 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.44 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.43 |
| ▸ | GRK2 | P25098 | 1/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6780133 | 0.79 | MEN1 (0.60) | FFAR1FFAR4HDAC3HDAC1HDAC2 | |
| SCHEMBL17325764 | 0.79 | HTT (0.66) | ROCK2ROCK1 | |
| SCHEMBL28227000 | 0.77 | FFAR1 (0.52) | FFAR1FFAR4HDAC3HDAC1HDAC2 | |
| SCHEMBL6924151 | 0.76 | FFAR1 (0.58) | FFAR1FFAR4CYP11B1CYP11B2HDAC3 | |
| SCHEMBL14044097 | 0.76 | FFAR1 (0.66) | FFAR1FFAR4HDAC3HDAC1HDAC2 | |
| SCHEMBL6778391 | 0.76 | FFAR1 (0.55) | FFAR1FFAR4ALDH1A1 | |
| SCHEMBL22910534 | 0.75 | LTA4H (0.53) | CYP11B1CYP11B2KCNA5KCNH2DPP4 | |
| SCHEMBL11339286 | 0.75 | ADRA2B (0.49) | HDAC1F2ROCK2GRK2ADRA2B | |
| SCHEMBL27935474 | 0.74 | KCNA5 (0.55) | FFAR1FFAR4HDAC3HDAC1HDAC2 | |
| SCHEMBL2126955 | 0.74 | F2 (0.70) | HDAC1ALDH1A1F2PRSS1LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6780883-B2 | ANTICHOLESTEROL AGENTS; CARDIOVASCULAR DISORDERS; ANTILIPEMIC AGENTS; RESTENOSIS; DIETETICS | WARNER-LAMBERT COMPANY | 2004-08-24 | — | — | US | disclosed |