Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 16/20 | 0.54 |
| ▸ | S1PR3 | Q99500 | 7/20 | 0.49 |
| ▸ | PLAT | P00750 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6778666 | 0.90 | S1PR1 (0.57) | S1PR1S1PR3PLATNPC1RAB9A | |
| SCHEMBL6780851 | 0.86 | S1PR1 (0.55) | S1PR1S1PR3PLATNPC1RAB9A | |
| SCHEMBL6780809 | 0.86 | S1PR1 (0.67) | S1PR1S1PR3PLATNPC1RAB9A | |
| SCHEMBL6777362 | 0.85 | S1PR1 (0.58) | S1PR1S1PR3NPC1RAB9AHTT | |
| SCHEMBL6776628 | 0.84 | S1PR1 (0.57) | S1PR1S1PR3NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6785923 | 0.83 | S1PR1 (0.61) | S1PR1S1PR3NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6782004 | 0.82 | S1PR1 (0.56) | S1PR1S1PR3PLATNPC1RAB9A | |
| SCHEMBL6782031 | 0.80 | GRM5 (0.51) | S1PR1S1PR3PLATNPC1RAB9A | |
| SCHEMBL6781308 | 0.80 | S1PR1 (0.51) | S1PR1S1PR3PLATNPC1RAB9A | |
| SCHEMBL6786217 | 0.80 | NPC1 (0.59) | S1PR1S1PR3PLATNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6521610-B2 | For controlling harmful insects, acarina and nematodes | HOECHST SCHERING AGREVO GMBH (DE) | 2003-02-18 | — | — | US | claimed |
| US-20020013326-A1 | 4-Haloalkyl-3-heterocyclylpyridines and 4-haloalkyl-5-heterocyclyl-pyrimidines, processes for their preparation, compositions comprising them, and their use as pesticides | TIEBES JORG (DE) | 2002-01-31 | — | — | US | claimed |
| US-6239160-B1 | 4-haloalkyl-3-heterocyclylpyridines and 4-haloalkyl-5-heterocyclylpyrimidines, processes for their preparation, compositions comprising them, and their use as pesticides | HOECHST SCHERING AGREVO GMBH (DE) | 2001-05-29 | — | — | US | claimed |
| EP-0991648-A1 | 4-HALOALKYL-3- HETEROCYCLYLPYRIDINES AND 4-HALOALKYL -5-HETEROCYCLYLPYRIDINES, METHOD FOR THE PRODUCTION THEREOF, AGENTS CONTAINING THE SAME AND THEIR USE AS PESTICIDES | Hoechst Schering AgrEvo GmbH (DE) | 2000-04-12 | — | — | EP | claimed |
| WO-1998057969-A1 | 4-HALOALKYL-3- HETEROCYCLYLPYRIDINES AND 4-HALOALKYL -5-HETEROCYCLYLPYRIDINES, METHOD FOR THE PRODUCTION THEREOF, AGENTS CONTAINING THE SAME AND THEIR USE AS PESTICIDES | HOECHST SCHERING AGREVO GMBH (DE) | 1998-12-23 | — | — | WO | claimed |
| US-6699853-B2 | PROTECTING USEFUL PLANTS AGAINST THE UNDESIRABLE ACTION OF HARMFUL INSECTS, ACARIDS AND NEMATODES, | HOECHST SCHERING AGREVO GMBH (DE) | 2004-03-02 | — | — | US | disclosed |
| US-20030162812-A1 | 4-haloalkyl-3-heterocyclylpyridines, 4-haloalkyl-5-heterocyclyl-pyrimidines and 4-trifluoromethyl-3-oxadiazolylpyridines, processes for their preparation, compositions comprising them, and their use as pesticides | HARMSEN SVEN (DE) | 2003-08-28 | — | — | US | disclosed |
| US-6521610-B2 | For controlling harmful insects, acarina and nematodes | HOECHST SCHERING AGREVO GMBH (DE) | 2003-02-18 | — | — | US | disclosed |
| US-20020013326-A1 | 4-Haloalkyl-3-heterocyclylpyridines and 4-haloalkyl-5-heterocyclyl-pyrimidines, processes for their preparation, compositions comprising them, and their use as pesticides | TIEBES JORG (DE) | 2002-01-31 | — | — | US | disclosed |
| US-6239160-B1 | 4-haloalkyl-3-heterocyclylpyridines and 4-haloalkyl-5-heterocyclylpyrimidines, processes for their preparation, compositions comprising them, and their use as pesticides | HOECHST SCHERING AGREVO GMBH (DE) | 2001-05-29 | — | — | US | disclosed |
| EP-0991648-A1 | 4-HALOALKYL-3- HETEROCYCLYLPYRIDINES AND 4-HALOALKYL -5-HETEROCYCLYLPYRIDINES, METHOD FOR THE PRODUCTION THEREOF, AGENTS CONTAINING THE SAME AND THEIR USE AS PESTICIDES | Hoechst Schering AgrEvo GmbH (DE) | 2000-04-12 | — | — | EP | disclosed |
| WO-1998057969-A1 | 4-HALOALKYL-3- HETEROCYCLYLPYRIDINES AND 4-HALOALKYL -5-HETEROCYCLYLPYRIDINES, METHOD FOR THE PRODUCTION THEREOF, AGENTS CONTAINING THE SAME AND THEIR USE AS PESTICIDES | HOECHST SCHERING AGREVO GMBH (DE) | 1998-12-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030162812-A1 | 4-haloalkyl-3-heterocyclylpyridines, 4-haloalkyl-5-heterocyclyl-pyrimidines and 4-trifluoromethyl-3-oxadiazolylpyridines, processes for their preparation, compositions comprising them, and their use as pesticides | DDT, HCK, HPD | S1PR1 2943/4885S1PR3 1664/4885PLAT 604/4885 |
| US-20020013326-A1 | 4-Haloalkyl-3-heterocyclylpyridines and 4-haloalkyl-5-heterocyclyl-pyrimidines, processes for their preparation, compositions comprising them, and their use as pesticides | DDT, HAX1, HDHD5 | S1PR1 3032/4885S1PR3 2382/4885PLAT 2209/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.