SCHEMBL7016302

SCHEMBL7016302

NC(Cc1c[nH]c2cnccc12)C(=O)O

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.66
KDM4E B2RXH2 4/20 0.66
MAPT P10636 4/20 0.66
LMNA P02545 3/20 0.66
BLM P54132 3/20 0.66
PMP22 Q01453 3/20 0.66
MEN1 O00255 3/20 0.66
TSHR P16473 2/20 0.66
HIF1A Q16665 2/20 0.66
MPO P05164 1/20 0.66
CYP3A4 P08684 3/20 0.58
HSD17B10 Q99714 3/20 0.58
ALDH1A1 P00352 2/20 0.58
ALOX15 P16050 2/20 0.58
NFKB1 P19838 2/20 0.58
NPSR1 Q6W5P4 2/20 0.58
HTR1A P08908 1/20 0.58
ADORA3 P0DMS8 1/20 0.58
HTR2A P28223 1/20 0.58
HTR2C P28335 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31370083 1.00 KMT2A (0.66) KMT2AKDM4EMAPTLMNABLM
SCHEMBL1897795 1.00 KMT2A (0.66) KMT2AKDM4EMAPTLMNABLM
SCHEMBL25356181 0.89 KMT2A (0.66) KMT2AKDM4EMAPTLMNABLM
SCHEMBL31369404 0.89 KMT2A (0.66) KMT2AKDM4EMAPTLMNABLM
SCHEMBL17337919 0.89 KMT2A (0.66) KMT2AKDM4EMAPTLMNABLM
SCHEMBL31267234 0.89 KMT2A (0.66) KMT2AKDM4EMAPTLMNABLM
SCHEMBL31267200 0.89 KMT2A (0.66) KMT2AKDM4EMAPTLMNABLM
Water SCHEMBL8021055 0.88 KMT2A (0.64) KMT2AKDM4EMAPTLMNABLM
SCHEMBL6780792 0.84 TACR1 (0.47) KMT2AKDM4EMAPTLMNABLM
Dl-Tryptophan SCHEMBL28121864 0.81 KDM4E (0.84) KMT2AKDM4EMAPTLMNABLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240344032-A1 ORGANOID PRODUCTION METHOD, CULTURE MEDIUM FOR ORGANOID PRODUCTION, ORGANOID, AND TEST SUBSTANCE EVALUATION METHOD JSR CORPORATION (JP) 2024-10-17 US claimed
CN-117957310-A Method for producing organoid, culture medium for organoid production, organoid, and method for evaluating test substance JSR株式会社 2024-04-30 CN claimed
US-20250222146-A1 Radiopharmaceuticals Targeting Somatostatin Receptor 2 and Uses Thereof RAYZEBIO, INC. (US) 2025-07-10 US disclosed
WO-2025137443-A1 RADIOPHARMACEUTICAL COMPOSITIONS TARGETING SOMATOSTATIN RECEPTORS AND USES THEREOF RAYZEBIO, INC. (US) 2025-06-26 WO disclosed
WO-2025137441-A1 RADIOPHARMACEUTICALS TARGETING SOMATOSTATIN RECEPTOR 2 AND USES THEREOF RAYZEBIO, INC. (US) 2025-06-26 WO disclosed
US-20240344032-A1 ORGANOID PRODUCTION METHOD, CULTURE MEDIUM FOR ORGANOID PRODUCTION, ORGANOID, AND TEST SUBSTANCE EVALUATION METHOD JSR CORPORATION (JP) 2024-10-17 US disclosed
EP-4426676-A2 METHODS FOR THE PRODUCTION OF TRYPTOPHANS, TRYPTAMINES, INTERMEDIATES, SIDE PRODUCTS AND DERIVATIVES MIAMI UNIVERSITY (US) 2024-09-11 EP disclosed
CN-118201966-A Human transferrin receptor binding antibody-peptide conjugates 肽梦想株式会社 2024-06-14 CN disclosed
WO-2023081837-A9 METHODS FOR THE PRODUCTION OF TRYPTOPHANS, TRYPTAMINES, INTERMEDIATES, SIDE PRODUCTS AND DERIVATIVES MIAMI UNIVERSITY (US) 2024-03-14 WO disclosed
US-20230203098-A1 HUMAN TRANSFERRIN RECEPTOR BINDING PEPTIDE JCR PHARMACEUTICALS CO., LTD. (JP) 2023-06-29 US disclosed
WO-2023081837-A2 METHODS FOR THE PRODUCTION OF TRYPTOPHANS, TRYPTAMINES, INTERMEDIATES, SIDE PRODUCTS AND DERIVATIVES MIAMI UNIVERSITY (US) 2023-05-11 WO disclosed
CN-114401732-A CD38 binding agents and uses thereof 克莱奥药品有限公司 2022-04-26 CN disclosed
US-8465981-B2 Polypeptides, systems, and methods useful for detecting glucose UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) 2013-06-18 US disclosed
US-8465981-B2 Polypeptides, systems, and methods useful for detecting glucose UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) 2013-06-18 US disclosed
US-20110117661-A1 POLYPEPTIDES, SYSTEMS, AND METHODS USEFUL FOR DETECTING GLUCOSE UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION 2011-05-19 US disclosed
US-20110117661-A1 POLYPEPTIDES, SYSTEMS, AND METHODS USEFUL FOR DETECTING GLUCOSE UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION 2011-05-19 US disclosed
EP-1255757-B1 AMINO ACID DERIVATIVES AND USE THEREOF AS NEP, ACE AND ECE INHIBITORS INST NAT SANTE RECH MED (FR) 2003-06-18 EP disclosed
EP-1255757-A1 AMINO ACID DERIVATIVES AND USE THEREOF AS NEP, ACE AND ECE INHIBITORS INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) 2002-11-13 EP disclosed
WO-2001060822-A1 AMINO ACID DERIVATIVES AND USE THEREOF AS NEP, ACE AND ECE INHIBITORS INSTITUT NATIONAL DE LA RECHERCHE MEDICALE INSERM (FR) 2001-08-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110117661-A1 POLYPEPTIDES, SYSTEMS, AND METHODS USEFUL FOR DETECTING GLUCOSE IAPP, GCKR, GID4 KMT2A 4693/4885KDM4E 4775/4885MAPT 3747/4885
US-20230203098-A1 HUMAN TRANSFERRIN RECEPTOR BINDING PEPTIDE TFRC, SLC3A2, SLC7A1 KMT2A 2608/4885KDM4E 3553/4885MAPT 972/4885
US-20250222146-A1 Radiopharmaceuticals Targeting Somatostatin Receptor 2 and Uses Thereof SSTR2, SSTR4, SSTR5 KMT2A 1730/4885KDM4E 3869/4885MAPT 3475/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.