Sugi Predict

Sugi Predict / Compounds / SCHEMBL1897795

SCHEMBL1897795

SCHEMBL1897795

N[C@@H](Cc1c[nH]c2cnccc12)C(=O)O

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 4/20 0.66
▸ KDM4E B2RXH2 4/20 0.66
▸ MAPT P10636 4/20 0.66
▸ LMNA P02545 3/20 0.66
▸ BLM P54132 3/20 0.66
▸ PMP22 Q01453 3/20 0.66
▸ MEN1 O00255 3/20 0.66
▸ TSHR P16473 2/20 0.66
▸ HIF1A Q16665 2/20 0.66
▸ MPO P05164 1/20 0.66
▸ CYP3A4 P08684 3/20 0.58
▸ HSD17B10 Q99714 3/20 0.58
▸ ALDH1A1 P00352 2/20 0.58
▸ ALOX15 P16050 2/20 0.58
▸ NFKB1 P19838 2/20 0.58
▸ NPSR1 Q6W5P4 2/20 0.58
▸ HTR1A P08908 1/20 0.58
▸ ADORA3 P0DMS8 1/20 0.58
▸ HTR2A P28223 1/20 0.58
▸ HTR2C P28335 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7016302 1.00 KMT2A (0.66) KMT2AKDM4EMAPTLMNABLM
SCHEMBL31370083 1.00 KMT2A (0.66) KMT2AKDM4EMAPTLMNABLM
SCHEMBL25356181 0.89 KMT2A (0.66) KMT2AKDM4EMAPTLMNABLM
SCHEMBL31369404 0.89 KMT2A (0.66) KMT2AKDM4EMAPTLMNABLM
SCHEMBL17337919 0.89 KMT2A (0.66) KMT2AKDM4EMAPTLMNABLM
SCHEMBL31267234 0.89 KMT2A (0.66) KMT2AKDM4EMAPTLMNABLM
SCHEMBL31267200 0.89 KMT2A (0.66) KMT2AKDM4EMAPTLMNABLM
Water SCHEMBL8021055 0.88 KMT2A (0.64) KMT2AKDM4EMAPTLMNABLM
SCHEMBL6780792 0.84 TACR1 (0.47) KMT2AKDM4EMAPTLMNABLM
Dl-Tryptophan SCHEMBL28121864 0.81 KDM4E (0.84) KMT2AKDM4EMAPTLMNABLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117957310-A Method for producing organoid, culture medium for organoid production, organoid, and method for evaluating test substance JSR株式会社 2024-04-30 — — CN claimed
EP-4720087-A1 PEPTIDE INHIBITORS OF INTERLEUKIN-23 RECEPTOR Zealand Pharma A/S (DK) 2026-04-08 — — EP disclosed
WO-2025128626-A1 HYBRID PEPTIDE COMPOUNDS HAVING A MODIFIED LYSINE RESIDUE CARMOT THERAPEUTICS, INC. (US) 2025-06-19 — — WO disclosed
WO-2025128624-A2 HYBRID PEPTIDE COMPOUNDS HAVING A SUBSTITUTED TRYPTOPHAN RESIDUE OR A TERMINAL SUBSTITUENT CARMOT THERAPEUTICS, INC. (US) 2025-06-19 — — WO disclosed
WO-2024246269-A1 PEPTIDE INHIBITORS OF INTERLEUKIN-23 RECEPTOR ZEALAND PHARMA A/S (DK) 2024-12-05 — — WO disclosed
US-20240390508-A1 HUMAN TRANSFERRIN RECEPTOR BINDING PEPTIDE-DRUG CONJUGATE TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2024-11-28 — — US disclosed
US-20240344032-A1 ORGANOID PRODUCTION METHOD, CULTURE MEDIUM FOR ORGANOID PRODUCTION, ORGANOID, AND TEST SUBSTANCE EVALUATION METHOD JSR CORPORATION (JP) 2024-10-17 — — US disclosed
EP-4426676-A2 METHODS FOR THE PRODUCTION OF TRYPTOPHANS, TRYPTAMINES, INTERMEDIATES, SIDE PRODUCTS AND DERIVATIVES MIAMI UNIVERSITY (US) 2024-09-11 — — EP disclosed
EP-4410958-A1 ORGANOID PRODUCTION METHOD, CULTURE MEDIUM FOR ORGANOID PRODUCTION, ORGANOID, AND TEST SUBSTANCE EVALUATION METHOD JSR Corporation (JP) 2024-08-07 — — EP disclosed
EP-4389893-A1 HUMAN TRANSFERRIN RECEPTOR BINDING PEPTIDE-DRUG CONJUGATE Takeda Pharmaceutical Company Limited (JP) 2024-06-26 — — EP disclosed
CN-118201966-A Human transferrin receptor binding antibody-peptide conjugates 肽梦想株式会社 2024-06-14 — — CN disclosed
CN-117957310-A Method for producing organoid, culture medium for organoid production, organoid, and method for evaluating test substance JSR株式会社 2024-04-30 — — CN disclosed
WO-2023081837-A9 METHODS FOR THE PRODUCTION OF TRYPTOPHANS, TRYPTAMINES, INTERMEDIATES, SIDE PRODUCTS AND DERIVATIVES MIAMI UNIVERSITY (US) 2024-03-14 — — WO disclosed
WO-2023081837-A2 METHODS FOR THE PRODUCTION OF TRYPTOPHANS, TRYPTAMINES, INTERMEDIATES, SIDE PRODUCTS AND DERIVATIVES MIAMI UNIVERSITY (US) 2023-05-11 — — WO disclosed
CN-115151556-A Human transferrin receptor binding peptides JCR制药股份有限公司 2022-10-04 — — CN disclosed
CN-114401732-A CD38 binding agents and uses thereof 克莱奥药品有限公司 2022-04-26 — — CN disclosed
US-8465981-B2 Polypeptides, systems, and methods useful for detecting glucose UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) 2013-06-18 — — US disclosed
US-20110117661-A1 POLYPEPTIDES, SYSTEMS, AND METHODS USEFUL FOR DETECTING GLUCOSE UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION 2011-05-19 — — US disclosed
WO-2009021052-A1 POLYPEPTIDES, SYSTEMS, AND METHODS USEFUL FOR DETECTING GLUCOSE UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) 2009-02-12 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240390508-A1 HUMAN TRANSFERRIN RECEPTOR BINDING PEPTIDE-DRUG CONJUGATE MUSK, TFRC, SLC7A1 KMT2A 3558/4885KDM4E 2530/4885MAPT 2855/4885
US-20110117661-A1 POLYPEPTIDES, SYSTEMS, AND METHODS USEFUL FOR DETECTING GLUCOSE IAPP, GCKR, GID4 KMT2A 4693/4885KDM4E 4775/4885MAPT 3747/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.