Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 3/20 | 0.38 |
| ▸ | NPY5R | Q15761 | 5/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.34 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HRH2 | P25021 | 1/20 | 0.34 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6780196 | 0.88 | TLR7 (0.37) | KCNH2TLR7ADORA2ACA12CA1 | |
| SCHEMBL6281980 | 0.85 | CA12 (0.34) | NPY5RTLR7ADORA2ACA12CA1 | |
| SCHEMBL6778610 | 0.84 | ALDH1A1 (0.38) | KCNH2TLR7ADORA2ACA12CA1 | |
| SCHEMBL6779152 | 0.82 | TLR7 (0.40) | KCNH2TLR7ADORA2ALMNAPOLB | |
| SCHEMBL6783971 | 0.82 | ALDH1A1 (0.44) | TLR7LMNAALDH1A1HTR1A | |
| SCHEMBL6779513 | 0.81 | ALDH1A1 (0.38) | TLR7ADORA2ACA12CA1CA2 | |
| SCHEMBL14516477 | 0.81 | GRIA1 (0.35) | GRIA1NPY5RKCNH2TLR7ADORA2A | |
| SCHEMBL4791709 | 0.80 | ALDH1A1 (0.36) | KCNH2TLR7ADORA2ALMNAPOLB | |
| SCHEMBL4793952 | 0.79 | ALDH1A1 (0.38) | KCNH2TLR7ADORA2ALMNAPOLB | |
| SCHEMBL6774053 | 0.79 | HDAC1 (0.41) | TLR7LMNAALDH1A1HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100372846-C | Sulfonamido substituted imidazopyridines | 3M INNOVATIVE PROPERTIES CO (US) | 2008-03-05 | — | — | CN | claimed |
| US-6696465-B2 | INDUCING BIOSYNTHESIS OF CYTOKINES; VIRAL AND NEOPLASTIC DISEASES | 3M INNOVATIVE PROPERTIES COMPANY | 2004-02-24 | — | — | US | claimed |