Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.36 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 3/20 | 0.35 |
| ▸ | CA2 | P00918 | 3/20 | 0.35 |
| ▸ | CA9 | Q16790 | 3/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | ILK | Q13418 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6783971 | 0.91 | ALDH1A1 (0.44) | ALDH1A1TLR7HTR1APKMCYP24A1 | |
| SCHEMBL6779745 | 0.89 | ALDH1A1 (0.51) | ALDH1A1L3MBTL1HTR1APKMCYP24A1 | |
| SCHEMBL6774053 | 0.89 | HDAC1 (0.41) | ALDH1A1TLR7HTR1APKMCYP24A1 | |
| SCHEMBL6781246 | 0.89 | HTR7 (0.39) | ALDH1A1HTR1ACA2CA1 | |
| SCHEMBL6777208 | 0.87 | DRD2 (0.41) | ALDH1A1L3MBTL1PKM | |
| SCHEMBL6287653 | 0.85 | F2 (0.39) | ALDH1A1CA12CA2CA9MEN1 | |
| SCHEMBL6287659 | 0.85 | F2 (0.39) | ALDH1A1CA12CA2CA9MEN1 | |
| SCHEMBL6780196 | 0.84 | TLR7 (0.37) | ALDH1A1TLR7CA12CA2CA9 | |
| SCHEMBL6778222 | 0.84 | ALDH1A1 (0.40) | ALDH1A1L3MBTL1HTR1AKMT2A | |
| SCHEMBL6784710 | 0.82 | GLO1 (0.38) | L3MBTL1PKMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100372846-C | Sulfonamido substituted imidazopyridines | 3M INNOVATIVE PROPERTIES CO (US) | 2008-03-05 | — | — | CN | claimed |
| US-6696465-B2 | INDUCING BIOSYNTHESIS OF CYTOKINES; VIRAL AND NEOPLASTIC DISEASES | 3M INNOVATIVE PROPERTIES COMPANY | 2004-02-24 | — | — | US | claimed |