Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 4/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.40 |
| ▸ | TMIGD3 | P0DMS9 | 4/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HRH2 | P25021 | 1/20 | 0.36 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6783971 | 0.88 | ALDH1A1 (0.44) | TLR7ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL6780196 | 0.87 | TLR7 (0.37) | TLR7ADORA2ATMIGD3ADORA1ALDH1A1 | |
| SCHEMBL6774053 | 0.84 | HDAC1 (0.41) | TLR7ALDH1A1LMNAKDM4E | |
| SCHEMBL6778610 | 0.83 | ALDH1A1 (0.38) | TLR7ADORA2ATMIGD3ADORA1ALDH1A1 | |
| SCHEMBL6780833 | 0.82 | GRIA1 (0.38) | TLR7ADORA2AALDH1A1LMNAPOLB | |
| SCHEMBL6281980 | 0.82 | CA12 (0.34) | TLR7ADORA2AALDH1A1KMT2ALMNA | |
| SCHEMBL6773010 | 0.82 | ALDH1A1 (0.43) | ADORA2ATMIGD3ADORA1ALDH1A1HPGD | |
| SCHEMBL6777563 | 0.82 | SCN1A (0.49) | TLR7ALDH1A1HTR2AKDM4E | |
| SCHEMBL6779513 | 0.81 | ALDH1A1 (0.38) | TLR7ADORA2AADORA1ALDH1A1MEN1 | |
| SCHEMBL6774160 | 0.81 | HPGD (0.47) | ADORA2ATMIGD3ADORA1HPGDADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6696465-B2 | INDUCING BIOSYNTHESIS OF CYTOKINES; VIRAL AND NEOPLASTIC DISEASES | 3M INNOVATIVE PROPERTIES COMPANY | 2004-02-24 | — | — | US | claimed |