Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | LCK | P06239 | 6/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | METAP1 | P53582 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6781725 | 0.85 | PI4KB (0.39) | PI4KBMAPTKDM4EHSD17B10SIRT1 | |
| SCHEMBL28234278 | 0.81 | PI4KB (0.45) | PI4KBMAPTKDM4EHSD17B10SIRT1 | |
| SCHEMBL1136868 | 0.81 | PI4KB (0.45) | PI4KBMAPTKDM4EHSD17B10SIRT1 | |
| SCHEMBL25305926 | 0.80 | PI4KB (0.44) | PI4KBMAPTKDM4EHSD17B10SIRT1 | |
| SCHEMBL11103983 | 0.79 | PI4KB (0.43) | PI4KBMAPTKDM4EHSD17B10SIRT1 | |
| Bicarbonate SCHEMBL10807004 | 0.77 | PI4KB (0.42) | PI4KBMAPTKDM4EHSD17B10SIRT1 | |
| Bicarbonate SCHEMBL10809756 | 0.77 | PI4KB (0.42) | PI4KBMAPTKDM4EHSD17B10SIRT1 | |
| SCHEMBL11108424 | 0.75 | PI4KB (0.43) | PI4KBMAPTKDM4EHSD17B10SIRT1 | |
| SCHEMBL24435469 | 0.74 | ALDH1A1 (0.45) | PI4KBMAPTKDM4EHSD17B10SIRT1 | |
| Bicarbonate SCHEMBL10809440 | 0.74 | PI4KB (0.40) | PI4KBMAPTKDM4EHSD17B10SIRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6815459-B2 | USE IN PREVENTING VARIOUS MEDICAL DYSFUNCTIONS AND DISEASES ARISING FROM REACTIVE OXYGEN SPECIES, IN PARTICULAR STROKE, PARKINSON'S DISEASE, ALZHEIMER'S DISEASE; LIPID PEROXIDATION INHIBITION ACTIVITY | SAM-SUNG ELECTRONICS CO., LTD. (KR) | 2004-11-09 | — | — | US | disclosed |
| US-20030220337-A1 | Seleno compounds containing nitrone moiety, their preparation and their therapeutic uses | SAM-SUNG ELECTRONICS CO., LTD. (KR) | 2003-11-27 | — | — | US | disclosed |
| WO-2003010154-A1 | SELENO COMPOUNDS CONTAINING NITRONE MOIETY, THEIR PREPARATION AND THEIR THERAPEUTIC USES | SAMSUNG ELECTRONICS CO. LTD. (KR) | 2003-02-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030220337-A1 | Seleno compounds containing nitrone moiety, their preparation and their therapeutic uses | GPX4, GPX1, LPO | PI4KB 2325/4885MAPT 124/4885KDM4E 4378/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.