SCHEMBL678158

SCHEMBL678158

NC(Cc1ccc(O)cc1)C(=O)NC(Cc1ccc(O)cc1)C(=O)NC(Cc1ccc(O)cc1)C(=O)NC(Cc1ccc(O)cc1)C(=O)O

nearest known ligand 0.61

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 1/20 0.61
MME P08473 2/20 0.58
YARS1 P54577 2/20 0.57
ACE P12821 1/20 0.56
CPA1 P15085 1/20 0.56
ACE2 Q9BYF1 1/20 0.56
NPY1R P25929 1/20 0.56
NPY2R P49146 1/20 0.56
NPY4R P50391 1/20 0.56
OPRM1 P35372 3/20 0.56
ENPEP Q07075 2/20 0.56
OPRD1 P41143 2/20 0.56
OPRK1 P41145 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9419220 1.00 SLC7A5 (0.61) SLC7A5MMEYARS1ACECPA1
SCHEMBL10789173 1.00 SLC7A5 (0.61) SLC7A5MMEYARS1ACECPA1
SCHEMBL678159 1.00 SLC7A5 (0.61) SLC7A5MMEYARS1ACECPA1
SCHEMBL30839475 1.00 SLC7A5 (0.61) SLC7A5MMEYARS1ACECPA1
SCHEMBL29657676 1.00 SLC7A5 (0.61) SLC7A5MMEYARS1ACECPA1
SCHEMBL31025673 0.97 SLC7A5 (0.65) SLC7A5MMEYARS1ACECPA1
SCHEMBL1574161 0.97 SLC7A5 (0.65) SLC7A5MMEYARS1ACECPA1
SCHEMBL30439955 0.97 SLC7A5 (0.65) SLC7A5MMEYARS1ACECPA1
SCHEMBL27653020 0.97 SLC7A5 (0.65) SLC7A5MMEYARS1ACECPA1
SCHEMBL1574158 0.97 SLC7A5 (0.65) SLC7A5MMEYARS1ACECPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8940791-B2 Acetylated amino acids as anti-platelet agents, nutritional and vitamin supplements SIGNATURE R&D HOLDINGS, LLC (US) 2015-01-27 US disclosed
EP-2789341-A2 O-acetylated amino acids as anti-platelet agents and nutritional supplements Chandran, V. Ravi (US) 2014-10-15 EP disclosed
US-20140200256-A1 Acetylated amino acids as Anti-platelet agents, Nutritional And Vitamin Supplements SIGNATURE R&D HOLDINGS, LLC (US) 2014-07-17 US disclosed
US-20110312890-A1 ACETYLATED AMINO ACIDS AS ANTI-PLATELET AGENTS, NUTRITIONAL AND VITAMIN SUPPLEMENTS SIGNATURE R&D HOLDINGS, LLC (US) 2011-12-22 US disclosed
US-20110275713-A1 Acetylated amino acids as Anti-platelet agents, Nutritional And Vitamin Supplements SIGNATURE R&D HOLDINGS, LLC (US) 2011-11-10 US disclosed
US-8003683-B2 Acetylated amino acids as anti-platelet agents, nutritional and vitamin supplements SIGNATURE R&D HOLDINGS, LLC (US) 2011-08-23 US disclosed
EP-1957066-A2 ACETYLATED AMINO ACIDS AS ANTI-PLATELET AGENTS, NUTRITIONAL AND VITAMIN SUPPLEMENTS Chandran, V. Ravi (US) 2008-08-20 EP disclosed
WO-2007059047-A2 ACETYLATED AMINO ACIDS AS ANTI-PLATELET AGENTS, NUTRITIONAL AND VITAMIN SUPPLEMENTS CHANDRAN V RAVI (US) 2007-05-24 WO disclosed
US-20070112060-A1 Acetylated amino acids as anti-platelet agents, nutritional and vitamin supplements SIGNATURE R&D HOLDINGS, LLC 2007-05-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140200256-A1 Acetylated amino acids as Anti-platelet agents, Nutritional And Vitamin Supplements PLTP, GP6, PDGFA SLC7A5 500/4885MME 2430/4885YARS1 3232/4885
US-20110312890-A1 ACETYLATED AMINO ACIDS AS ANTI-PLATELET AGENTS, NUTRITIONAL AND VITAMIN SUPPLEMENTS PLTP, GP6, PDGFA SLC7A5 500/4885MME 2430/4885YARS1 3232/4885
US-20070112060-A1 Acetylated amino acids as anti-platelet agents, nutritional and vitamin supplements PLTP, GP6, PDGFA SLC7A5 500/4885MME 2430/4885YARS1 3232/4885
US-20110275713-A1 Acetylated amino acids as Anti-platelet agents, Nutritional And Vitamin Supplements PLTP, GP6, PDGFA SLC7A5 500/4885MME 2430/4885YARS1 3232/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.