SCHEMBL678210

SCHEMBL678210

CC(Cc1ccc(C(=O)Oc2ccccc2)cc1)[Sb](C)C

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARG P37231 7/20 0.46
PPARA Q07869 7/20 0.46
MAPT P10636 3/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
CTSL P07711 1/20 0.46
PARP10 Q53GL7 1/20 0.45
PRSS1 P07477 1/20 0.44
ACR P10323 1/20 0.44
TMPRSS15 P98073 1/20 0.44
ALDH1A1 P00352 4/20 0.44
HPGD P15428 1/20 0.44
TSHR P16473 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
PKM P14618 1/20 0.43
KMT2A Q03164 1/20 0.43
CCNC P24863 1/20 0.43
CDK8 P49336 1/20 0.43
GAA P10253 1/20 0.43
PPARD Q03181 3/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1790172 0.85 MAPT (0.50) MAPTSMN1; SMN2CTSLPARP10PRSS1
SCHEMBL9369179 0.83 SRD5A2 (0.51) PPARGPPARAMAPTSMN1; SMN2CTSL
SCHEMBL678420 0.82 MAPT (0.48) MAPTSMN1; SMN2CTSLPARP10PRSS1
SCHEMBL9373057 0.81 PDCD1 (0.50) PPARGPPARAMAPTSMN1; SMN2CTSL
SCHEMBL678295 0.80 PPARG (0.50) PPARGPPARASMN1; SMN2ALDH1A1HPGD
SCHEMBL677813 0.80 LOXL2 (0.54) MAPTSMN1; SMN2ALDH1A1HPGDTSHR
SCHEMBL28290868 0.80 MAPT (0.46) PPARGPPARAMAPTSMN1; SMN2CTSL
SCHEMBL465959 0.80 MAPT (0.49) MAPTSMN1; SMN2CTSLPARP10PRSS1
SCHEMBL677037 0.79 MAPT (0.50) MAPTSMN1; SMN2PARP10PRSS1ACR
SCHEMBL17236371 0.79 KMT2A (0.55) MAPTCTSLPARP10ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110275774-A1 ORGANOANTIMONY COMPOUND, PROCESS FOR PREPARING SAME, LIVING RADICAL POLYMERIZATION INITIATOR, PROCESS FOR PRODUCING POLYMER WITH USE OF SAME, AND THE POLYMER YAMAGO SHIGERU 2011-11-10 US disclosed
US-8008414-B2 Organic antimony compound, process for producing the same, living radical polymerization initiator, process for producing polymer using the same, and polymer OTSUKA CHEMICAL CO., LTD. (JP) 2011-08-30 US disclosed
EP-1767539-B1 ORGANIC ANTIMONY COMPOUND, PROCESS FOR PRODUCING THE SAME, LIVING RADICAL POLYMERIZATION INITIATOR, PROCESS FOR PRODUCING POLYMER USING THE SAME, AND POLYMER OTSUKA CHEMICAL CO LTD (JP) 2011-07-27 EP disclosed
US-20090299008-A1 Organic antimony compound, process for producing the same, living radical polymerization initiator, process for producing polymer using the same, and polymer OTSUKA CHEMICAL CO., LTD. (JP) 2009-12-03 US disclosed
EP-1767539-A1 ORGANIC ANTIMONY COMPOUND, PROCESS FOR PRODUCING THE SAME, LIVING RADICAL POLYMERIZATION INITIATOR, PROCESS FOR PRODUCING POLYMER USING THE SAME, AND POLYMER OTSUKA CHEMICAL COMPANY, LTD. (JP) 2007-03-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090299008-A1 Organic antimony compound, process for producing the same, living radical polymerization initiator, process for producing polymer using the same, and polymer AOC2, ODC1, MCM7 PPARG 4044/4885PPARA 4005/4885MAPT 2424/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.