SCHEMBL678295

SCHEMBL678295

CC(Cc1ccc(C(=O)c2ccccc2)cc1)[Sb](C)C

nearest known ligand 0.50

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
PPARG P37231 2/20 0.50
PPARD Q03181 1/20 0.50
PPARA Q07869 1/20 0.50
MDM2 Q00987 1/20 0.47
ALDH1A1 P00352 5/20 0.47
RAB9A P51151 4/20 0.46
SRD5A2 P31213 4/20 0.46
HPGD P15428 3/20 0.45
HTT P42858 2/20 0.45
SMN1; SMN2 Q16637 2/20 0.45
NPSR1 Q6W5P4 1/20 0.45
ELANE P08246 1/20 0.45
NPC1 O15118 2/20 0.45
SIGMAR1 Q99720 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
ATM Q13315 1/20 0.44
LMNA P02545 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5018743 0.82 PTGS1 (0.55) PPARGPPARDPPARAALDH1A1RAB9A
SCHEMBL677891 0.82 SIGMAR1 (0.56) SIGMAR1
SCHEMBL678342 0.81 KMT2A (0.53) PPARGPPARAALDH1A1RAB9AHPGD
SCHEMBL678210 0.80 PPARG (0.46) PPARGPPARDPPARAALDH1A1HPGD
SCHEMBL23654947 0.79 PPARG (0.52) PPARGPPARDPPARAALDH1A1RAB9A
SCHEMBL13471981 0.79 TAAR1 (0.62) PPARGPPARDPPARAALDH1A1RAB9A
SCHEMBL10071094 0.79 PPARG (0.52) PPARGPPARDPPARAALDH1A1RAB9A
SCHEMBL2334247 0.79 ALDH1A1 (0.50) PPARGPPARDPPARAMDM2ALDH1A1
SCHEMBL15391739 0.77 MDM2 (0.60) PPARGPPARDPPARAMDM2ALDH1A1
SCHEMBL465620 0.77 ALDH1A1 (0.47) PPARGPPARDPPARAMDM2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110275774-A1 ORGANOANTIMONY COMPOUND, PROCESS FOR PREPARING SAME, LIVING RADICAL POLYMERIZATION INITIATOR, PROCESS FOR PRODUCING POLYMER WITH USE OF SAME, AND THE POLYMER YAMAGO SHIGERU 2011-11-10 US disclosed
US-8008414-B2 Organic antimony compound, process for producing the same, living radical polymerization initiator, process for producing polymer using the same, and polymer OTSUKA CHEMICAL CO., LTD. (JP) 2011-08-30 US disclosed
EP-1767539-B1 ORGANIC ANTIMONY COMPOUND, PROCESS FOR PRODUCING THE SAME, LIVING RADICAL POLYMERIZATION INITIATOR, PROCESS FOR PRODUCING POLYMER USING THE SAME, AND POLYMER OTSUKA CHEMICAL CO LTD (JP) 2011-07-27 EP disclosed
US-20090299008-A1 Organic antimony compound, process for producing the same, living radical polymerization initiator, process for producing polymer using the same, and polymer OTSUKA CHEMICAL CO., LTD. (JP) 2009-12-03 US disclosed
EP-1767539-A1 ORGANIC ANTIMONY COMPOUND, PROCESS FOR PRODUCING THE SAME, LIVING RADICAL POLYMERIZATION INITIATOR, PROCESS FOR PRODUCING POLYMER USING THE SAME, AND POLYMER OTSUKA CHEMICAL COMPANY, LTD. (JP) 2007-03-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090299008-A1 Organic antimony compound, process for producing the same, living radical polymerization initiator, process for producing polymer using the same, and polymer AOC2, ODC1, MCM7 PPARG 4044/4885PPARD 4732/4885PPARA 4005/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.