Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 7/20 | 0.42 |
| ▸ | PDE4A | P27815 | 6/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 6/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 6/20 | 0.42 |
| ▸ | PDE5A | O76074 | 5/20 | 0.38 |
| ▸ | PDE3B | Q13370 | 5/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 5/20 | 0.38 |
| ▸ | PDE1A | P54750 | 4/20 | 0.38 |
| ▸ | PDE1B | Q01064 | 4/20 | 0.38 |
| ▸ | PDE1C | Q14123 | 4/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA4 | P22748 | 2/20 | 0.37 |
| ▸ | CA6 | P23280 | 2/20 | 0.37 |
| ▸ | CA7 | P43166 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16077681 | 0.85 | CA12 (0.55) | PDE4DPDE4APDE4BPDE4CCA12 | |
| SCHEMBL14732689 | 0.85 | LMNA (0.55) | PDE4DPDE4APDE4BPDE4CCYP3A4 | |
| SCHEMBL10354178 | 0.83 | MEN1 (0.46) | PDE4DPDE4APDE4BPDE4CCA12 | |
| SCHEMBL15171954 | 0.83 | MAPT (0.45) | PDE4DPDE4APDE4BPDE4CCA12 | |
| SCHEMBL16884962 | 0.81 | ALDH1A1 (0.47) | PDE4DPDE4APDE4BPDE4CCA1 | |
| SCHEMBL17708318 | 0.81 | PDE4A (0.40) | PDE4DPDE4APDE4BPDE4CPDE5A | |
| SCHEMBL408803 | 0.81 | HTR2A (0.43) | PDE4DPDE4APDE4BPDE4CPDE5A | |
| SCHEMBL129806 | 0.78 | PDE4A (0.41) | PDE4DPDE4APDE4BPDE4CPDE5A | |
| SCHEMBL13304426 | 0.75 | TP53 (0.51) | MEN1KMT2ARXFP1ALDH1A1 | |
| SCHEMBL13418645 | 0.74 | HTT (0.43) | PDE4DPDE4APDE4BPDE4CTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240239730-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING MONOTERPENES | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2024-07-18 | — | — | US | disclosed |
| US-9700524-B2 | Pharmaceutical compositions comprising monoterpenes | NEONC TECHNOLOGIES INC. (US) | 2017-07-11 | — | — | US | disclosed |
| US-20170088494-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING MONOTERPENES | NATIONAL INSTITUTES OF HEALTH | 2017-03-30 | — | — | US | disclosed |
| US-9498448-B2 | Pharmaceutical compositions comprising monoterpenes | NeOne Technologies, Inc. (US) | 2016-11-22 | — | — | US | disclosed |
| US-20160332942-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING MONOTERPENES | UNIVERSITY OF SOUTHERN CALIFORNIA | 2016-11-17 | — | — | US | disclosed |
| US-9480659-B2 | Pharmaceutical compositions comprising monoterpenes | Neonc Technologies, Inc. (US) | 2016-11-01 | — | — | US | disclosed |
| US-20160158162-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING MONOTERPENES | UNIVERSITY OF SOUTHERN CALIFORNIA | 2016-06-09 | — | — | US | disclosed |
| US-20160039730-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING MONOTERPENES | UNIVERSITY OF SOUTHERN CALIFORNIA | 2016-02-11 | — | — | US | disclosed |
| US-20150368173-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING MONOTERPENES | UNIVERSITY OF SOUTHERN CALIFORNIA | 2015-12-24 | — | — | US | disclosed |
| US-9133085-B2 | Pharmaceutical compositions comprising monoterpenes | NEONC TECHNOLOGIES INC (US) | 2015-09-15 | — | — | US | disclosed |
| US-8889678-B2 | Acyl guanidine derivatives modulating the hedgehog protein signaling pathway | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2014-11-18 | — | — | US | disclosed |
| US-20130303807-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING MONOTERPENES | UNIVERSITY OF SOUTHERN CALIFORNIA | 2013-11-14 | — | — | US | disclosed |
| US-8507734-B2 | Pharmaceutical compositions comprising monoterpenes | NEONC TECHNOLOGIES INC. (US) | 2013-08-13 | — | — | US | disclosed |
| US-20120196865-A1 | Acyl Guanidine Derivatives Modulating The Hedgehog Protein Signaling Pathway | UNIVERSITE DE STRASBOURG (FR) | 2012-08-02 | — | — | US | disclosed |
| US-20110280860-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING MONOTERPENES | NEONC TECHNOLOGIES INC. | 2011-11-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160332942-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING MONOTERPENES | SQLE, DHPS, GGPS1 | PDE4D 1319/4885PDE4A 1217/4885PDE4B 894/4885 |
| US-20120196865-A1 | Acyl Guanidine Derivatives Modulating The Hedgehog Protein Signaling Pathway | SHH, GLI1, SMO | PDE4D 211/4885PDE4A 262/4885PDE4B 310/4885 |
| US-20240239730-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING MONOTERPENES | SQLE, DHPS, GGPS1 | PDE4D 1319/4885PDE4A 1217/4885PDE4B 894/4885 |
| US-20110280860-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING MONOTERPENES | SQLE, DHPS, GGPS1 | PDE4D 1319/4885PDE4A 1217/4885PDE4B 894/4885 |
| US-20160158162-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING MONOTERPENES | SQLE, DHPS, GGPS1 | PDE4D 1319/4885PDE4A 1217/4885PDE4B 894/4885 |
| US-20150368173-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING MONOTERPENES | SQLE, DHPS, GGPS1 | PDE4D 1319/4885PDE4A 1217/4885PDE4B 894/4885 |
| US-20160039730-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING MONOTERPENES | SQLE, DHPS, GGPS1 | PDE4D 1319/4885PDE4A 1217/4885PDE4B 894/4885 |
| US-20170088494-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING MONOTERPENES | SQLE, DHPS, GGPS1 | PDE4D 1319/4885PDE4A 1217/4885PDE4B 894/4885 |
| US-20130303807-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING MONOTERPENES | SQLE, DHPS, GGPS1 | PDE4D 1319/4885PDE4A 1217/4885PDE4B 894/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.