Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QDPR | P09417 | 2/20 | 0.48 |
| ▸ | HTR1D | P28221 | 2/20 | 0.44 |
| ▸ | ASAH1 | Q13510 | 3/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | NAAA | Q02083 | 1/20 | 0.40 |
| ▸ | TLR9 | Q9NR96 | 3/20 | 0.40 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.40 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.39 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 3/20 | 0.37 |
| ▸ | LSS | P48449 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 2/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6741343 | 0.84 | SLC6A2 (0.48) | HTR1DASAH1DRD2SLC6A4MAPK11 | |
| SCHEMBL6741065 | 0.78 | HTR6 (0.53) | HTR1DTLR9TLR8TLR7MAPK11 | |
| SCHEMBL6742251 | 0.74 | HTR6 (0.52) | DRD2HTR6 | |
| SCHEMBL7253016 | 0.73 | HTR1D (0.76) | QDPRHTR1DHTR6LSS | |
| SCHEMBL6843375 | 0.73 | QDPR (0.43) | QDPRHTR1DASAH1FAAHNAAA | |
| SCHEMBL14571688 | 0.73 | QDPR (0.53) | QDPRASAH1FAAHNAAATLR9 | |
| SCHEMBL6743107 | 0.72 | MAPK11 (0.35) | HTR1DSLC6A4MAPK11MAPK14 | |
| SCHEMBL17683262 | 0.72 | HTR1D (0.49) | QDPRHTR1DDRD2SLC6A4MAPK11 | |
| SCHEMBL28296478 | 0.71 | QDPR (0.43) | QDPRTLR9TLR8TLR7HTR6 | |
| SCHEMBL10268348 | 0.70 | SLC6A4 (0.69) | QDPRDRD2SLC6A4HTR6LSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6716837-B1 | INDOLE AND INDAZOLE COMPOUNDS | NPS ALLELIX BIOPHARMACEUTICALS, INC. (CA) | 2004-04-06 | — | — | US | disclosed |