Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QDPR | P09417 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 6/20 | 0.42 |
| ▸ | TLR9 | Q9NR96 | 7/20 | 0.40 |
| ▸ | TLR8 | Q9NR97 | 7/20 | 0.40 |
| ▸ | TLR7 | Q9NYK1 | 7/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.38 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | USP7 | Q93009 | 1/20 | 0.37 |
| ▸ | KHK | P50053 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23442948 | 0.81 | SLC6A2 (0.49) | QDPRHTR2CTLR9TLR8TLR7 | |
| SCHEMBL29891558 | 0.81 | SLC6A2 (0.49) | QDPRHTR2CTLR9TLR8TLR7 | |
| SCHEMBL28298164 | 0.77 | QDPR (0.43) | QDPRHTR2CTLR9TLR8TLR7 | |
| SCHEMBL28296431 | 0.75 | DRD2 (0.43) | QDPRHTR2CTLR9TLR8TLR7 | |
| SCHEMBL28296619 | 0.74 | HTR2C (0.41) | QDPRHTR2CTLR9TLR8TLR7 | |
| SCHEMBL24999103 | 0.73 | HTR6 (0.30) | BRD4CREBBPHTR6 | |
| SCHEMBL5584815 | 0.72 | QDPR (0.46) | QDPRHTR2CTLR9TLR8TLR7 | |
| SCHEMBL6782259 | 0.71 | QDPR (0.48) | QDPRTLR9TLR8TLR7HTR6 | |
| SCHEMBL23411317 | 0.69 | MAPK14 (0.47) | QDPRHTR2CTLR9TLR8TLR7 | |
| Hydrochloric Acid SCHEMBL30567988 | 0.69 | PDE1C (0.45) | QDPRHTR2CTLR9TLR8TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109923108-A | Pyridyl-substituted indole compounds | 百时美施贵宝公司 | 2019-06-21 | — | — | CN | disclosed |