SCHEMBL678254

SCHEMBL678254

CC(=O)OC(=O)C1CCCN1O

nearest known ligand 0.36

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.36
CHRM2 P08172 3/20 0.34
MEN1 O00255 1/20 0.34
CYP2D6 P10635 1/20 0.34
KMT2A Q03164 1/20 0.34
CHRM1 P11229 1/20 0.34
ALDH1A1 P00352 1/20 0.33
TSHR P16473 1/20 0.33
RAB9A P51151 1/20 0.32
CTSL P07711 1/20 0.30
CTSB P07858 1/20 0.30
CTSH P09668 1/20 0.30
CTSK P43235 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8385960 1.00 POLB (0.36) POLBCHRM2MEN1CYP2D6KMT2A
SCHEMBL200913 0.80 POLB (0.49) POLB
SCHEMBL389987 0.80 POLB (0.49) POLB
SCHEMBL4109077 0.80 POLB (0.49) POLB
SCHEMBL29138427 0.79 POLB (0.45) POLBCHRM2CHRM1RAB9A
Hydrochloric Acid SCHEMBL5159954 0.78 POLB (0.47) POLB
Hydrochloric Acid SCHEMBL2337448 0.78 POLB (0.47) POLB
Hydrochloric Acid SCHEMBL3055388 0.78 POLB (0.47) POLB
SCHEMBL13252795 0.77
SCHEMBL6427888 0.77 SRC (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8940791-B2 Acetylated amino acids as anti-platelet agents, nutritional and vitamin supplements SIGNATURE R&D HOLDINGS, LLC (US) 2015-01-27 US disclosed
EP-2789341-A2 O-acetylated amino acids as anti-platelet agents and nutritional supplements Chandran, V. Ravi (US) 2014-10-15 EP disclosed
US-20140200256-A1 Acetylated amino acids as Anti-platelet agents, Nutritional And Vitamin Supplements SIGNATURE R&D HOLDINGS, LLC (US) 2014-07-17 US disclosed
US-20110312890-A1 ACETYLATED AMINO ACIDS AS ANTI-PLATELET AGENTS, NUTRITIONAL AND VITAMIN SUPPLEMENTS SIGNATURE R&D HOLDINGS, LLC (US) 2011-12-22 US disclosed
US-20110275713-A1 Acetylated amino acids as Anti-platelet agents, Nutritional And Vitamin Supplements SIGNATURE R&D HOLDINGS, LLC (US) 2011-11-10 US disclosed
US-8003683-B2 Acetylated amino acids as anti-platelet agents, nutritional and vitamin supplements SIGNATURE R&D HOLDINGS, LLC (US) 2011-08-23 US disclosed
EP-1957066-A2 ACETYLATED AMINO ACIDS AS ANTI-PLATELET AGENTS, NUTRITIONAL AND VITAMIN SUPPLEMENTS Chandran, V. Ravi (US) 2008-08-20 EP disclosed
WO-2007059047-A2 ACETYLATED AMINO ACIDS AS ANTI-PLATELET AGENTS, NUTRITIONAL AND VITAMIN SUPPLEMENTS CHANDRAN V RAVI (US) 2007-05-24 WO disclosed
US-20070112060-A1 Acetylated amino acids as anti-platelet agents, nutritional and vitamin supplements SIGNATURE R&D HOLDINGS, LLC 2007-05-17 US disclosed
EP-0910351-A1 PARTICLES COMPRISING AMPHIPHILIC COPOLYMERS, HAVING A CROSS-LINKED SHELL DOMAIN AND AN INTERIOR CORE DOMAIN, USEFUL FOR PHARMACEUTICAL AND OTHER APPLICATIONS G.D. Searle & Co. (US) 1999-04-28 EP disclosed
EP-0907666-A1 PARTICLES COMPRISING AMPHIPHILIC COPOLYMERS, HAVING A CROSS-LINKED SHELL DOMAIN AND AN INTERIOR CORE DOMAIN, USEFUL FOR PHARMACEUTICAL AND OTHER APPLICATIONS G.D. Searle & Co. (US) 1999-04-14 EP disclosed
WO-1997049736-A2 PARTICLES COMPRISING AMPHIPHILIC COPOLYMERS, HAVING A CROSS-LINKED SHELL DOMAIN AND AN INTERIOR CORE DOMAIN, USEFUL FOR PHARMACEUTICAL AND OTHER APPLICATIONS G.D. SEARLE AND CO. (US) 1997-12-31 WO disclosed
WO-1997049387-A1 PARTICLES COMPRISING AMPHIPHILIC COPOLYMERS, HAVING A CROSS-LINKED SHELL DOMAIN AND AN INTERIOR CORE DOMAIN, USEFUL FOR PHARMACEUTICAL AND OTHER APPLICATIONS G.D. SEARLE AND CO. (US) 1997-12-31 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140200256-A1 Acetylated amino acids as Anti-platelet agents, Nutritional And Vitamin Supplements PLTP, GP6, PDGFA POLB 3209/4885CHRM2 3988/4885MEN1 3872/4885
US-20110312890-A1 ACETYLATED AMINO ACIDS AS ANTI-PLATELET AGENTS, NUTRITIONAL AND VITAMIN SUPPLEMENTS PLTP, GP6, PDGFA POLB 3209/4885CHRM2 3988/4885MEN1 3872/4885
US-20070112060-A1 Acetylated amino acids as anti-platelet agents, nutritional and vitamin supplements PLTP, GP6, PDGFA POLB 3209/4885CHRM2 3988/4885MEN1 3872/4885
US-20110275713-A1 Acetylated amino acids as Anti-platelet agents, Nutritional And Vitamin Supplements PLTP, GP6, PDGFA POLB 3209/4885CHRM2 3988/4885MEN1 3872/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.