SCHEMBL678288

SCHEMBL678288

CC(c1ccc(O)cc1)[Sb](C)C

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 10/20 0.56
ESR2 Q92731 9/20 0.56
PDCD1 Q15116 1/20 0.56
CD274 Q9NZQ7 1/20 0.56
LMNA P02545 2/20 0.44
CYP3A4 P08684 2/20 0.44
MAPT P10636 2/20 0.44
ALOX15 P16050 2/20 0.44
CYP2C9 P11712 2/20 0.44
TDP1 Q9NUW8 2/20 0.44
CYP1A2 P05177 1/20 0.44
PGR P06401 1/20 0.44
CHRM2 P08172 1/20 0.44
ADORA3 P0DMS8 1/20 0.44
AR P10275 1/20 0.44
CYP2D6 P10635 1/20 0.44
CHRM1 P11229 1/20 0.44
DRD1 P21728 1/20 0.44
TBXA2R P21731 1/20 0.44
PTGS1 P23219 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20448417 0.87 ESR1 (0.35) ESR1ESR2PDCD1CD274TYR
SCHEMBL2145868 0.75 ADRB2 (0.52) LMNATDP1SLC6A2SLC6A3HIF1A
SCHEMBL30753092 0.73 ESR1 (0.68) ESR1ESR2PDCD1CD274LMNA
SCHEMBL29351491 0.73 ESR1 (0.68) ESR1ESR2PDCD1CD274LMNA
SCHEMBL10593295 0.73 ESR1 (1.00) ESR1ESR2PDCD1CD274LMNA
SCHEMBL11949347 0.73 ESR1 (0.68) ESR1ESR2PDCD1CD274LMNA
SCHEMBL4247422 0.73 ESR1 (0.68) ESR1ESR2PDCD1CD274LMNA
SCHEMBL26946 0.73 ESR1 (1.00) ESR1ESR2PDCD1CD274LMNA
SCHEMBL28954 0.73 ESR1 (0.68) ESR1ESR2PDCD1CD274LMNA
Hydroquinone SCHEMBL9580215 0.73 ESR1 (0.68) ESR1ESR2PDCD1CD274LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110275774-A1 ORGANOANTIMONY COMPOUND, PROCESS FOR PREPARING SAME, LIVING RADICAL POLYMERIZATION INITIATOR, PROCESS FOR PRODUCING POLYMER WITH USE OF SAME, AND THE POLYMER YAMAGO SHIGERU 2011-11-10 US disclosed
US-8008414-B2 Organic antimony compound, process for producing the same, living radical polymerization initiator, process for producing polymer using the same, and polymer OTSUKA CHEMICAL CO., LTD. (JP) 2011-08-30 US disclosed
EP-1767539-B1 ORGANIC ANTIMONY COMPOUND, PROCESS FOR PRODUCING THE SAME, LIVING RADICAL POLYMERIZATION INITIATOR, PROCESS FOR PRODUCING POLYMER USING THE SAME, AND POLYMER OTSUKA CHEMICAL CO LTD (JP) 2011-07-27 EP disclosed
US-20090299008-A1 Organic antimony compound, process for producing the same, living radical polymerization initiator, process for producing polymer using the same, and polymer OTSUKA CHEMICAL CO., LTD. (JP) 2009-12-03 US disclosed
EP-1767539-A1 ORGANIC ANTIMONY COMPOUND, PROCESS FOR PRODUCING THE SAME, LIVING RADICAL POLYMERIZATION INITIATOR, PROCESS FOR PRODUCING POLYMER USING THE SAME, AND POLYMER OTSUKA CHEMICAL COMPANY, LTD. (JP) 2007-03-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090299008-A1 Organic antimony compound, process for producing the same, living radical polymerization initiator, process for producing polymer using the same, and polymer AOC2, ODC1, MCM7 ESR1 1315/4885ESR2 3082/4885PDCD1 3429/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.