Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 6/20 | 0.39 |
| ▸ | LSS | P48449 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6778259 | 0.89 | KDM4E (0.39) | MEN1USP2ESR1CYP1A2CYP3A4 | |
| SCHEMBL6780037 | 0.88 | CYP3A4 (0.40) | MEN1USP2ESR1CYP1A2CYP3A4 | |
| SCHEMBL6773797 | 0.86 | KMT2A (0.43) | MEN1USP2ESR1CYP1A2CYP3A4 | |
| SCHEMBL6774446 | 0.85 | ALDH1A1 (0.46) | USP2 | |
| SCHEMBL6778251 | 0.85 | MEN1 (0.43) | HSD11B1MEN1USP2ESR1CYP1A2 | |
| SCHEMBL6778198 | 0.84 | CA1 (0.40) | CYP19A1HSD11B1MEN1USP2ESR1 | |
| SCHEMBL6780526 | 0.84 | MEP1B (0.41) | MEN1USP2ESR1CYP1A2CYP3A4 | |
| SCHEMBL6779845 | 0.83 | KDM4E (0.38) | KMT2ABRPF1 | |
| SCHEMBL6779678 | 0.82 | NPY5R (0.40) | MEN1USP2ESR1CYP1A2CYP3A4 | |
| SCHEMBL6778211 | 0.82 | ALDH1A1 (0.50) | MEN1USP2ESR1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6696465-B2 | INDUCING BIOSYNTHESIS OF CYTOKINES; VIRAL AND NEOPLASTIC DISEASES | 3M INNOVATIVE PROPERTIES COMPANY | 2004-02-24 | — | — | US | claimed |