SCHEMBL67837

SCHEMBL67837

COc1ccc(S(=O)(=O)Cl)cc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PKM P14618 4/20 0.67
CA1 P00915 3/20 0.55
CA2 P00918 3/20 0.55
MMP2 P08253 2/20 0.55
MMP8 P22894 2/20 0.55
MMP13 P45452 2/20 0.55
MMP1 P03956 1/20 0.55
MMP9 P14780 1/20 0.55
GAA P10253 1/20 0.55
NPC1 O15118 1/20 0.53
PKLR P30613 1/20 0.53
RAB9A P51151 1/20 0.53
CA9 Q16790 2/20 0.52
CA12 O43570 1/20 0.52
CA7 P43166 1/20 0.52
CA14 Q9ULX7 1/20 0.52
ALDH1A1 P00352 2/20 0.50
PTGS2 P35354 1/20 0.50
F2 P00734 1/20 0.50
PRSS1 P07477 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6108870 1.00 PKM (0.67) PKMCA1CA2MMP2MMP8
SCHEMBL793287 0.94 PKM (0.59) PKMCA1CA2MMP2MMP8
SCHEMBL924893 0.94 PKM (0.59) PKMCA1CA2MMP2MMP8
Methylene Chloride SCHEMBL28109382 0.94 PKM (0.59) PKMCA1CA2MMP2MMP8
SCHEMBL8093585 0.85 APP (0.55) PKMCA1CA2GAANPC1
Anisole SCHEMBL3037045 0.85 LTA4H (0.62) PKMMMP2MMP8MMP13MMP9
1,4-Dimethoxybenzene SCHEMBL5960077 0.85 CA1 (0.65) PKMCA1CA2MMP2MMP8
SCHEMBL2875518 0.85 PKM (0.48) PKMCA1CA2MMP2MMP8
Anisole SCHEMBL22187427 0.85 ALDH1A1 (0.67) PKMGAAALDH1A1HTTHSD17B10
SCHEMBL3685320 0.84 ALDH1A1 (0.63) PKMCA1CA2MMP2MMP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 5101 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122010846-A 1-Phenyl-1H-benzo [ d ] imidazole compound serving as FLT3 kinase inhibitor, preparation method, pharmaceutical composition and application 天津医科大学 2026-05-12 CN claimed
US-12383535-B2 Hydrogen peroxide-responsive KEAP1-NRF2 ppi inhibitor prodrug, and preparation method therefor CHINA PHARMACEUTICAL UNIVERSITY (CN) 2025-08-12 US claimed
US-12258343-B2 Method for preparing 2-[(3R)-3-methylmorpholin-4-yl]-4-[1-methyl-1H-pyrazol-5-yl)-8-(1H-pyrazol-5-yl)-1,7-naphthyridine BAYER AKTIENGESELLSCHAFT (DE) 2025-03-25 US claimed
EP-3042645-B2 Dental composites with improved storage stability IVOCLAR VIVADENT AG (LI) 2025-03-12 EP claimed
CN-119490439-A Preparation method of arylsulfonyl amino quaternary ammonium salt antibacterial agent 苏州华道生物药业股份有限公司 2025-02-21 CN claimed
CN-119350315-A 2- (1H-indole-2-yl) -1,3, 4-oxadiazole derivatives, and preparation method and application thereof 南开大学 2025-01-24 CN claimed
US-12162883-B2 Process for the preparation of intermediates useful for making (2S,5R)-7-oxo-n-piperidin-4-yl-6-(sulfoxy)-1,6-diazabicyclo[3.2.1]octane-2-carboxamide MERCK SHARP & DOHME LLC (US) 2024-12-10 US claimed
CN-116283848-B Novel coronavirus nsp16 inhibitor, preparation method thereof, virtual screening method and application 中山大学 2024-12-10 CN claimed
CN-118955593-A Preparation method of 2' -alkoxy adenosine analogue 杭州中美华东制药有限公司 2024-11-15 CN claimed
CN-115703737-B Hydroxypyridones compound and application thereof as antibiotic sensitizer for overcoming bacterial biomembrane resistance 暨南大学 2024-09-24 CN claimed
WO-1999058578-A1 POLYMERISATION CATALYST BP CHEMICALS LIMITED (GB) 1999-11-18 WO claimed
EP-0576228-B1 Process for preparing beta-anomer enriched 2-deoxy-2,2-difluoro-D-ribofuranosyl-arylsulfonates LILLY CO ELI (US) 1999-02-03 EP claimed
US-5614628-A Process for the preparation of 9-amino camptothecin PHARMACIA & UPJOHN S.P.A. (IT) 1997-03-25 US claimed
EP-0576228-A1 Process for preparing beta-anomer enriched 2-deoxy-2,2-difluoro-D-ribofuranosyl-arylsulfonates ELI LILLY AND COMPANY (US) 1993-12-29 EP claimed
US-5252756-A Process for preparing beta-anomer enriched 2-deoxy-2,2-difluoro-D-ribofuranosyl-arylsulfonates ELI LILLY AND COMPANY (US) 1993-10-12 US claimed
EP-0170506-B1 METHOD FOR INVERSION OF OPTICALLY ACTIVE 4-HYDROXY-2-CYCLOPENTENONES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1991-03-20 EP claimed
US-4683323-A HYDROLYSIS OF SULFONIC ACID ESTER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1987-07-28 US claimed
EP-0170506-A2 Method for inversion of optically active 4-hydroxy-2-cyclopentenones SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1986-02-05 EP claimed
EP-0138720-A2 N-cyclisized benzenesulfone amides, process for their preparation and their use as active substances in pharmaceutical compositions DROPIC Société Civile de Gestion de Droit de Propriété Industrielle CHOAY (FR) 1985-04-24 EP claimed
US-4292191-A Activated peroxy compound bleaching compositions and bleaching detergent compositions COLGATE-PALMOLIVE COMPANY (US) 1981-09-29 US claimed