Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 4/20 | 0.45 |
| ▸ | CTSS | P25774 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.42 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 2/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | SYK | P43405 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6779105 | 1.00 | CTSK (0.45) | CTSKCTSSMAPTKMT2AKLK5 | |
| SCHEMBL13089877 | 0.88 | CTSK (0.48) | CTSKCTSSMAPTKMT2AKLK5 | |
| SCHEMBL14803932 | 0.82 | CTSK (0.50) | CTSKCTSSMAPTKMT2AKLK5 | |
| SCHEMBL13051340 | 0.82 | CTSK (0.50) | CTSKCTSSMAPTKMT2AKLK5 | |
| SCHEMBL31477252 | 0.81 | CTSK (0.43) | CTSKCTSSMAPTKMT2AKLK5 | |
| SCHEMBL12069800 | 0.81 | CTSK (0.49) | CTSKCTSSMAPTKMT2AKLK5 | |
| SCHEMBL12068193 | 0.81 | CTSK (0.49) | CTSKCTSSMAPTKMT2AKLK5 | |
| SCHEMBL6784979 | 0.81 | CTSK (0.49) | CTSKCTSSMAPTKMT2AKLK5 | |
| SCHEMBL30906712 | 0.81 | KMT2A (0.38) | CTSKCTSSMAPTKMT2AKLK5 | |
| SCHEMBL9077908 | 0.81 | CTSK (0.45) | CTSKCTSSMAPTKMT2AKLK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040005562-A9 | Comprises tranferase protein associated with biosynthesis of taxoids for treating breast and ovarian cancers | WASHINGTON STATE UNIVERSITY RESEARCH FOUNDATION | 2004-01-08 | — | — | US | disclosed |
| US-20030108891-A1 | Transacylases of the paclitaxel biosynthetic pathway | WASHINGTON STATE UNIVERSITY RESEARCH FOUNDATION | 2003-06-12 | — | — | US | disclosed |