Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 5/20 | 0.45 |
| ▸ | CTSS | P25774 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.41 |
| ▸ | SYK | P43405 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8563008 | 0.91 | CTSK (0.46) | CTSKCTSSMAPTATMCTSL | |
| SCHEMBL31477252 | 0.85 | CTSK (0.43) | CTSKCTSSMAPTKLK5ATM | |
| SCHEMBL13089877 | 0.84 | CTSK (0.48) | CTSKCTSSMAPTKLK5SYK | |
| SCHEMBL6784157 | 0.81 | CTSK (0.45) | CTSKCTSSMAPTKLK5SYK | |
| SCHEMBL6779105 | 0.81 | CTSK (0.45) | CTSKCTSSMAPTKLK5SYK | |
| SCHEMBL8426257 | 0.80 | PPARA (0.38) | CTSKCTSSMAPTATMGABRB1 | |
| SCHEMBL14803932 | 0.79 | CTSK (0.50) | CTSKCTSSMAPTKLK5ATM | |
| SCHEMBL13051340 | 0.79 | CTSK (0.50) | CTSKCTSSMAPTKLK5ATM | |
| SCHEMBL12069800 | 0.77 | CTSK (0.49) | CTSKCTSSMAPTKLK5ATM | |
| SCHEMBL6784979 | 0.77 | CTSK (0.49) | CTSKCTSSMAPTKLK5ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5556877-A | ANTITUMOR AGENTS | RHONE-POULENC RORER S.A. (FR) | 1996-09-17 | — | — | US | disclosed |