Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 8/20 | 0.46 |
| ▸ | CYP2E1 | P05181 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.43 |
| ▸ | GRM5 | P41594 | 1/20 | 0.43 |
| ▸ | FYN | P06241 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | USP8 | P40818 | 1/20 | 0.41 |
| ▸ | KARS1 | Q15046 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2731043 | 0.90 | CYP2A6 (0.44) | CYP2A6CYP2E1CYP2C9CYP2B6CYP2C19 | |
| SCHEMBL12278093 | 0.88 | CYP2A6 (0.48) | CYP2A6CYP2E1CYP2C9CYP2B6CYP2C19 | |
| SCHEMBL12278716 | 0.86 | CYP2A6 (0.51) | CYP2A6CYP2E1CYP2C9CYP2B6CYP2C19 | |
| SCHEMBL12279610 | 0.83 | USP8 (0.47) | CYP2A6CYP2E1CYP2C9CYP2B6CYP2C19 | |
| SCHEMBL12279439 | 0.80 | CYP2A6 (0.54) | CYP2A6CYP2E1CYP2C9CYP2B6CYP2C19 | |
| SCHEMBL13989135 | 0.80 | CYP2A6 (0.62) | CYP2A6CYP2E1CYP2C9CYP2B6CYP2C19 | |
| SCHEMBL12278130 | 0.76 | CYP2A6 (0.45) | CYP2A6CYP2E1CYP2C9CYP2B6CYP2C19 | |
| SCHEMBL28049612 | 0.76 | CYP2A6 (0.57) | CYP2A6CYP2E1CYP2C9CYP2B6CYP2C19 | |
| SCHEMBL12279662 | 0.75 | CYP2A6 (0.47) | CYP2A6CYP2E1CYP2C9CYP2B6CYP2C19 | |
| SCHEMBL12278719 | 0.75 | CYP2A6 (0.42) | CYP2A6CYP2E1CYP2C9CYP2B6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9451775-B2 | Heterocyclic compounds as pesticides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-09-27 | — | — | US | disclosed |
| US-9451775-B2 | Heterocyclic compounds as pesticides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-09-27 | — | — | US | disclosed |
| EP-2586312-B1 | Heterocyclic compounds as pest controllers | BAYER CROPSCIENCE AG (DE) | 2016-04-27 | — | — | EP | disclosed |
| US-20140336186-A1 | Heterocyclic Compounds as Pesticides | BAYER CORPSCIENCE AG (DE) | 2014-11-13 | — | — | US | disclosed |
| US-20140336186-A1 | Heterocyclic Compounds as Pesticides | BAYER CORPSCIENCE AG (DE) | 2014-11-13 | — | — | US | disclosed |
| US-8809547-B2 | Heterocyclic compounds as pesticides | BAYER CROPSCIENCE AG (DE) | 2014-08-19 | — | — | US | disclosed |
| US-8809547-B2 | Heterocyclic compounds as pesticides | BAYER CROPSCIENCE AG (DE) | 2014-08-19 | — | — | US | disclosed |
| EP-2591674-A1 | Heterocyclic compounds as pest controllers | Bayer CropScience AG (DE) | 2013-05-15 | — | — | EP | disclosed |
| EP-2586311-A1 | Heterocyclic compounds as pest controllers | Bayer CropScience AG (DE) | 2013-05-01 | — | — | EP | disclosed |
| EP-2586312-A1 | Heterocyclic compounds as pest controllers | Bayer CropScience AG (DE) | 2013-05-01 | — | — | EP | disclosed |
| EP-2583556-A1 | Heterocyclic compounds as pest controllers | Bayer CropScience AG (DE) | 2013-04-24 | — | — | EP | disclosed |
| EP-2583557-A1 | Heterocyclic compounds as pest controllers | Bayer CropScience AG (DE) | 2013-04-24 | — | — | EP | disclosed |
| US-20110275583-A1 | Synergistic active compound combinations | BAYER CROPSCIENCE AG (DE) | 2011-11-10 | — | — | US | disclosed |
| US-20110275583-A1 | Synergistic active compound combinations | BAYER CROPSCIENCE AG (DE) | 2011-11-10 | — | — | US | disclosed |
| WO-2011134964-A1 | SYNERGISTIC ACTIVE SUBSTANCE COMBINATIONS | BAYER CROPSCIENCE AG (DE) | 2011-11-03 | — | — | WO | disclosed |
| EP-2382865-A1 | Synergistic active agent compounds | Bayer CropScience AG (DE) | 2011-11-02 | — | — | EP | disclosed |
| US-20110212949-A1 | Heterocyclic Compounds as Pesticides | BAYER CROPSCIENCE AG | 2011-09-01 | — | — | US | disclosed |
| US-20110212949-A1 | Heterocyclic Compounds as Pesticides | BAYER CROPSCIENCE AG | 2011-09-01 | — | — | US | disclosed |
| WO-2010006713-A2 | HETEROCYCLIC COMPOUNDS USED AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2010-01-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110212949-A1 | Heterocyclic Compounds as Pesticides | DDT, ACHE, PTMS | CYP2A6 277/4885CYP2E1 26/4885CYP2C9 49/4885 |
| US-20140336186-A1 | Heterocyclic Compounds as Pesticides | DDT, ACHE, PTMS | CYP2A6 277/4885CYP2E1 26/4885CYP2C9 49/4885 |
| US-20110275583-A1 | Synergistic active compound combinations | ACHE, ACAT2, ACAT1 | CYP2A6 794/4885CYP2E1 531/4885CYP2C9 827/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.