Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.44 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6785331 | 0.83 | TP53 (0.52) | ABCB1MEN1KMT2ATP53MAPT | |
| SCHEMBL6781777 | 0.80 | TP53 (0.50) | ABCB1MEN1KMT2ATP53MAPT | |
| SCHEMBL6779429 | 0.79 | GLA (0.54) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL4135571 | 0.74 | POLB (0.45) | MEN1KMT2ATP53MAPT | |
| SCHEMBL1512508 | 0.74 | ADRA1D (0.53) | ADRA1DADRA1AADRA1B | |
| SCHEMBL707005 | 0.70 | KDM4E (0.69) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL2847409 | 0.70 | KDM4E (0.69) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| Hydrochloric Acid SCHEMBL1690850 | 0.69 | KDM4E (0.68) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| Hydrochloric Acid SCHEMBL2851355 | 0.69 | KDM4E (0.68) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL14563026 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0794178-A1 | QUINAZOLINE DERIVATIVE | NIPPON CHEMIPHAR CO., LTD. (JP) | 1997-09-10 | — | — | EP | disclosed |