SCHEMBL678625

SCHEMBL678625

C=Cc1ccc(OC)cc1.C=Cc1ccc(OC)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.58
CYP2A6 P11509 1/20 0.58
CA12 O43570 1/20 0.58
CA1 P00915 1/20 0.58
CA2 P00918 1/20 0.58
CA7 P43166 1/20 0.58
CA9 Q16790 1/20 0.58
CA14 Q9ULX7 1/20 0.58
CYP3A4 P08684 4/20 0.56
KDM4E B2RXH2 4/20 0.56
TP53 P04637 2/20 0.56
TSHR P16473 2/20 0.56
LMNA P02545 2/20 0.56
TRPA1 O75762 1/20 0.54
RELA Q04206 1/20 0.54
CYP1A2 P05177 3/20 0.52
CYP1A1 P04798 3/20 0.52
CYP1B1 Q16678 3/20 0.52
ESR1 P03372 2/20 0.52
ALOX15 P16050 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28436 1.00 ALDH1A1 (0.58) ALDH1A1CYP2A6CA12CA1CA2
SCHEMBL30496111 0.97 ALDH1A1 (0.56) ALDH1A1CYP2A6CA12CA1CA2
SCHEMBL28659476 0.97 ALDH1A1 (0.56) ALDH1A1CYP2A6CA12CA1CA2
Potassium SCHEMBL30719694 0.97 ALDH1A1 (0.56) ALDH1A1CYP2A6CA12CA1CA2
SCHEMBL7653257 0.97 ALDH1A1 (0.56) ALDH1A1CYP2A6CA12CA1CA2
Potassium SCHEMBL30719700 0.97 ALDH1A1 (0.56) ALDH1A1CYP2A6CA12CA1CA2
Potassium SCHEMBL30719693 0.97 ALDH1A1 (0.56) ALDH1A1CYP2A6CA12CA1CA2
SCHEMBL12567372 0.93 RELA (0.65) ALDH1A1CYP3A4KDM4ETP53TSHR
SCHEMBL1480961 0.93 ALDH1A1 (0.52) ALDH1A1CYP2A6CA12CA1CA2
SCHEMBL12516806 0.93 LTA4H (0.54) ALDH1A1CYP2A6CA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110275774-A1 ORGANOANTIMONY COMPOUND, PROCESS FOR PREPARING SAME, LIVING RADICAL POLYMERIZATION INITIATOR, PROCESS FOR PRODUCING POLYMER WITH USE OF SAME, AND THE POLYMER YAMAGO SHIGERU 2011-11-10 US disclosed
US-20060199927-A1 Process for production of living-radical polymers and polymers Outdoor Wireless Networks LLC 2006-09-07 US disclosed