Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 4/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.42 |
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 3/20 | 0.40 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.40 |
| ▸ | ABAT | P80404 | 2/20 | 0.39 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HTR3A | P46098 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | FNTA | P49354 | 1/20 | 0.36 |
| ▸ | FNTB | P49356 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16414794 | 1.00 | KDM4E (0.48) | KDM4EALDH1A1MAPTESR1ESR2 | |
| SCHEMBL16902817 | 0.86 | ESR1 (0.50) | KDM4EALDH1A1MAPTESR1ESR2 | |
| SCHEMBL16902821 | 0.84 | ESR1 (0.48) | KDM4EALDH1A1MAPTESR1ESR2 | |
| SCHEMBL448421 | 0.81 | ESR1 (0.55) | KDM4EALDH1A1MAPTESR1ESR2 | |
| SCHEMBL448422 | 0.81 | ESR1 (0.55) | KDM4EALDH1A1MAPTESR1ESR2 | |
| SCHEMBL105690 | 0.79 | ESR1 (0.52) | KDM4EALDH1A1MAPTESR1ESR2 | |
| SCHEMBL6423018 | 0.78 | TRPA1 (0.41) | IDO1TAAR1MAOBKMT2A | |
| SCHEMBL6423021 | 0.78 | TRPA1 (0.41) | IDO1TAAR1MAOBKMT2A | |
| SCHEMBL30753808 | 0.78 | AGXT (0.40) | MAPTIDO1CA2TAAR1MAOB | |
| SCHEMBL2300480 | 0.78 | AGXT (0.40) | MAPTIDO1CA2TAAR1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115120722-A | Use of SP/KLF transcription factor inhibitors | 天津医科大学 | 2022-09-30 | — | — | CN | claimed |
| US-20150031534-A1 | PESTICIDAL FLAVOBACTERIUM STRAIN AND BIOACTIVE COMPOSITIONS METABOLITES AND USES | PRO FARM GROUP, INC. | 2015-01-29 | — | — | US | claimed |
| CN-115120722-B | Use of SP/KLF transcription factor inhibitors | 天津医科大学 | 2024-02-09 | — | — | CN | disclosed |
| CN-111759827-B | A pharmaceutical composition for preventing or treating arthritis or inflammatory diseases | 忠北大学校产学协力团 | 2023-02-07 | — | — | CN | disclosed |
| CN-115120722-A | Use of SP/KLF transcription factor inhibitors | 天津医科大学 | 2022-09-30 | — | — | CN | disclosed |
| CN-107438433-B | Pharmaceutical composition for preventing and treating arthritis or inflammatory diseases containing 2-methoxy-4- (3- (4-methoxyphenyl) prop-1-en-1-yl) phenol as an active ingredient | 忠北大学校产学协力团 | 2021-06-25 | — | — | CN | disclosed |
| CN-107090414-B | Pesticidal flavobacterium strains | 马罗内生物创新公司 | 2020-12-04 | — | — | CN | disclosed |
| CN-111759827-A | A pharmaceutical composition for preventing or treating arthritis or inflammatory diseases | 忠北大学校产学协力团 | 2020-10-13 | — | — | CN | disclosed |
| CN-103382196-A | (E)-1-(8-benzopyranyl)-2-allyl-1-one and its analogues, and use thereof | UNIV SICHUAN | 2013-11-06 | — | — | CN | disclosed |
| US-6803367-B2 | ANTICANCER AGENTS; SYNERGISTIC MIXTURES | TAKARA SHUZO CO., LTD. (JP) | 2004-10-12 | — | — | US | disclosed |
| US-20030065014-A1 | Substance for inducing apoptosis | TAKARA BIO INC. (JP) | 2003-04-03 | — | — | US | disclosed |
| US-5459142-A | Autoimmune disease, atherosclerosis, antiischemic agents and nephritis | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-10-17 | — | — | US | disclosed |
| EP-0511879-B1 | Pyrazine derivatives | OTSUKA PHARMA CO LTD (JP) | 1995-03-22 | — | — | EP | disclosed |
| EP-0511879-A1 | Pyrazine derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1992-11-04 | — | — | EP | disclosed |
| US-4394496-A | POLYEPOXEDES WITH GOOD HIGH TEMPERATURE PROPERTIES | THE DOW CHEMICAL COMPANY (US) | 1983-07-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030065014-A1 | Substance for inducing apoptosis | BAX, BCL2, BAD | KDM4E 4256/4885ALDH1A1 1247/4885MAPT 3068/4885 |
| US-20150031534-A1 | PESTICIDAL FLAVOBACTERIUM STRAIN AND BIOACTIVE COMPOSITIONS METABOLITES AND USES | BLVRB, PRDX6, ACHE | KDM4E 3842/4885ALDH1A1 3340/4885MAPT 3804/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.